Persistent Microalbuminuria in Human Immunodeficiency Virus Infected Children in Kano, Nigeria
Microalbuminuria has been reported to be a precursor of HIV related renal disease, which if detected early and coupled with appropriate intervention may slow or retard the progress of the disease. One hundred and seventy-eight HIV infected children aged 15 years and below were recruited from the Pae...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2014/567838 |
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| author | Abdullahi Mudi Bashir U. Alhaj Fatimah Hassan-Hanga Isah Adagiri Yahaya |
| author_facet | Abdullahi Mudi Bashir U. Alhaj Fatimah Hassan-Hanga Isah Adagiri Yahaya |
| author_sort | Abdullahi Mudi |
| collection | DOAJ |
| description | Microalbuminuria has been reported to be a precursor of HIV related renal disease, which if detected early and coupled with appropriate intervention may slow or retard the progress of the disease. One hundred and seventy-eight HIV infected children aged 15 years and below were recruited from the Paediatric Infectious Disease Clinic of Aminu Kano Teaching Hospital (AKTH), Kano, to determine the prevalence of persistent microalbuminuria using the albumin creatinine ratio (ACR). Early morning urine samples and spot urine samples were analyzed using a dipstick specific for microalbumin. Those who tested positive had their samples reanalyzed in the laboratory using immunometric assay and Jaffe reaction method for albumin and creatinine, respectively. Patients that had ACR of 30–300 mg/g were said to have microalbuminuria and had their urine samples retested after 6 to 8 weeks. Twelve children (6.7%) had persistent microalbuminuria and had a mean age of 7.5±3.3 years, with a male to female ratio of 1 : 1. There was no significant relationship between the finding of microalbuminuria and age, sex, duration of infection, and the use of highly active antiretroviral therapy. Periodic screening for microalbuminuria using albumin specific dipstick should be considered for children with HIV infection. |
| format | Article |
| id | doaj-art-8c9e02c35581415da7cba4269f935494 |
| institution | Kabale University |
| issn | 2090-214X 2090-2158 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Nephrology |
| spelling | doaj-art-8c9e02c35581415da7cba4269f9354942025-02-03T06:14:12ZengWileyInternational Journal of Nephrology2090-214X2090-21582014-01-01201410.1155/2014/567838567838Persistent Microalbuminuria in Human Immunodeficiency Virus Infected Children in Kano, NigeriaAbdullahi Mudi0Bashir U. Alhaj1Fatimah Hassan-Hanga2Isah Adagiri Yahaya3Department of Paediatrics, Aminu Kano Teaching Hospital, PMB 3452, Kano, NigeriaDepartment of Paediatrics, Aminu Kano Teaching Hospital/Bayero University, PMB 3452, Kano, NigeriaDepartment of Paediatrics, Aminu Kano Teaching Hospital/Bayero University, PMB 3452, Kano, NigeriaDepartment of Chemical Pathology, Aminu Kano Teaching Hospital/Bayero University, PMB 3452, Kano, NigeriaMicroalbuminuria has been reported to be a precursor of HIV related renal disease, which if detected early and coupled with appropriate intervention may slow or retard the progress of the disease. One hundred and seventy-eight HIV infected children aged 15 years and below were recruited from the Paediatric Infectious Disease Clinic of Aminu Kano Teaching Hospital (AKTH), Kano, to determine the prevalence of persistent microalbuminuria using the albumin creatinine ratio (ACR). Early morning urine samples and spot urine samples were analyzed using a dipstick specific for microalbumin. Those who tested positive had their samples reanalyzed in the laboratory using immunometric assay and Jaffe reaction method for albumin and creatinine, respectively. Patients that had ACR of 30–300 mg/g were said to have microalbuminuria and had their urine samples retested after 6 to 8 weeks. Twelve children (6.7%) had persistent microalbuminuria and had a mean age of 7.5±3.3 years, with a male to female ratio of 1 : 1. There was no significant relationship between the finding of microalbuminuria and age, sex, duration of infection, and the use of highly active antiretroviral therapy. Periodic screening for microalbuminuria using albumin specific dipstick should be considered for children with HIV infection.http://dx.doi.org/10.1155/2014/567838 |
| spellingShingle | Abdullahi Mudi Bashir U. Alhaj Fatimah Hassan-Hanga Isah Adagiri Yahaya Persistent Microalbuminuria in Human Immunodeficiency Virus Infected Children in Kano, Nigeria International Journal of Nephrology |
| title | Persistent Microalbuminuria in Human Immunodeficiency Virus Infected Children in Kano, Nigeria |
| title_full | Persistent Microalbuminuria in Human Immunodeficiency Virus Infected Children in Kano, Nigeria |
| title_fullStr | Persistent Microalbuminuria in Human Immunodeficiency Virus Infected Children in Kano, Nigeria |
| title_full_unstemmed | Persistent Microalbuminuria in Human Immunodeficiency Virus Infected Children in Kano, Nigeria |
| title_short | Persistent Microalbuminuria in Human Immunodeficiency Virus Infected Children in Kano, Nigeria |
| title_sort | persistent microalbuminuria in human immunodeficiency virus infected children in kano nigeria |
| url | http://dx.doi.org/10.1155/2014/567838 |
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