Amyloid Accumulation in the Toxic Nodule of the Thyroid Gland in a Patient with End Stage Renal Failure

Amyloidosis is characterized by accumulation of amorphous, proteinaceous material in various organs and tissues of the body. Amyloid may accumulate in the thyroid gland in cases of medullary thyroid carcinoma and systemic amyloidosis. Amyloid accumulates extracellularly in the thyroid parenchyma and...

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Main Authors: Umut Mousa, Sema Aktas, Halit Uner
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2012/741754
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author Umut Mousa
Sema Aktas
Halit Uner
author_facet Umut Mousa
Sema Aktas
Halit Uner
author_sort Umut Mousa
collection DOAJ
description Amyloidosis is characterized by accumulation of amorphous, proteinaceous material in various organs and tissues of the body. Amyloid may accumulate in the thyroid gland in cases of medullary thyroid carcinoma and systemic amyloidosis. Amyloid accumulates extracellularly in the thyroid parenchyma and disrupts the normal follicular patterns. Most of the cases reported up to now were clinically euthyroid, but many presentation forms and overlaps have been reported. Herein we present a patient with toxic nodular goiter with amyloid deposition in the toxic nodule as well as the remaining thyroid tissue.
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institution Kabale University
issn 2090-6501
2090-651X
language English
publishDate 2012-01-01
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series Case Reports in Endocrinology
spelling doaj-art-8c9a06d287ef4ea1b714199d51b32dca2025-02-03T01:12:00ZengWileyCase Reports in Endocrinology2090-65012090-651X2012-01-01201210.1155/2012/741754741754Amyloid Accumulation in the Toxic Nodule of the Thyroid Gland in a Patient with End Stage Renal FailureUmut Mousa0Sema Aktas1Halit Uner2Department of Endocrinology and Metabolism, Baskent University Faculty of Medicine, 06500 Ankara, TurkeyDepartment of General Surgery, Baskent University Faculty of Medicine, 06500 Ankara, TurkeyDepartment of Pathology, Baskent University Faculty of Medicine, 06500 Ankara, TurkeyAmyloidosis is characterized by accumulation of amorphous, proteinaceous material in various organs and tissues of the body. Amyloid may accumulate in the thyroid gland in cases of medullary thyroid carcinoma and systemic amyloidosis. Amyloid accumulates extracellularly in the thyroid parenchyma and disrupts the normal follicular patterns. Most of the cases reported up to now were clinically euthyroid, but many presentation forms and overlaps have been reported. Herein we present a patient with toxic nodular goiter with amyloid deposition in the toxic nodule as well as the remaining thyroid tissue.http://dx.doi.org/10.1155/2012/741754
spellingShingle Umut Mousa
Sema Aktas
Halit Uner
Amyloid Accumulation in the Toxic Nodule of the Thyroid Gland in a Patient with End Stage Renal Failure
Case Reports in Endocrinology
title Amyloid Accumulation in the Toxic Nodule of the Thyroid Gland in a Patient with End Stage Renal Failure
title_full Amyloid Accumulation in the Toxic Nodule of the Thyroid Gland in a Patient with End Stage Renal Failure
title_fullStr Amyloid Accumulation in the Toxic Nodule of the Thyroid Gland in a Patient with End Stage Renal Failure
title_full_unstemmed Amyloid Accumulation in the Toxic Nodule of the Thyroid Gland in a Patient with End Stage Renal Failure
title_short Amyloid Accumulation in the Toxic Nodule of the Thyroid Gland in a Patient with End Stage Renal Failure
title_sort amyloid accumulation in the toxic nodule of the thyroid gland in a patient with end stage renal failure
url http://dx.doi.org/10.1155/2012/741754
work_keys_str_mv AT umutmousa amyloidaccumulationinthetoxicnoduleofthethyroidglandinapatientwithendstagerenalfailure
AT semaaktas amyloidaccumulationinthetoxicnoduleofthethyroidglandinapatientwithendstagerenalfailure
AT halituner amyloidaccumulationinthetoxicnoduleofthethyroidglandinapatientwithendstagerenalfailure