Somatostatin in inflammatory bowel disease
Intestinal inflammation is controlled by various immunomodulating cells, interacting by molecular mediators. Neuropeptides, released by enteric nerve cells and neuroendocrine mucosa cells, are able to affect several aspects of the general and intestinal immune system, with both pro- as well as anti-...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1997-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1080/09629359791424 |
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| _version_ | 1832549450651795456 |
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| author | J. D. Van Bergeijk J. H. P. Wilson |
| author_facet | J. D. Van Bergeijk J. H. P. Wilson |
| author_sort | J. D. Van Bergeijk |
| collection | DOAJ |
| description | Intestinal inflammation is controlled by various immunomodulating cells, interacting by molecular mediators. Neuropeptides, released by enteric nerve cells and neuroendocrine mucosa cells, are able to affect several aspects of the general and intestinal immune system, with both pro- as well as anti-inflammatory activities. In inflammatory bowel disease (IBD) there is both morphological as well as experimental evidence for involvement of neuropeptides in the pathogenesis. Somatostatin is the main inhibitory peptide in inflammatory processes, and its possible role in IBD is discussed. |
| format | Article |
| id | doaj-art-8c8e9c8e9ca14d1b98c7cf326c174bd9 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 1997-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-8c8e9c8e9ca14d1b98c7cf326c174bd92025-02-03T06:11:14ZengWileyMediators of Inflammation0962-93511466-18611997-01-0165-630330910.1080/09629359791424Somatostatin in inflammatory bowel diseaseJ. D. Van Bergeijk0J. H. P. Wilson1Department of Gastroenterology/Internal Medicine, University Hospital Dijkzigt, Rotterdam, The NetherlandsDepartment of Gastroenterology/Internal Medicine, University Hospital Dijkzigt, Rotterdam, The NetherlandsIntestinal inflammation is controlled by various immunomodulating cells, interacting by molecular mediators. Neuropeptides, released by enteric nerve cells and neuroendocrine mucosa cells, are able to affect several aspects of the general and intestinal immune system, with both pro- as well as anti-inflammatory activities. In inflammatory bowel disease (IBD) there is both morphological as well as experimental evidence for involvement of neuropeptides in the pathogenesis. Somatostatin is the main inhibitory peptide in inflammatory processes, and its possible role in IBD is discussed.http://dx.doi.org/10.1080/09629359791424 |
| spellingShingle | J. D. Van Bergeijk J. H. P. Wilson Somatostatin in inflammatory bowel disease Mediators of Inflammation |
| title | Somatostatin in inflammatory bowel disease |
| title_full | Somatostatin in inflammatory bowel disease |
| title_fullStr | Somatostatin in inflammatory bowel disease |
| title_full_unstemmed | Somatostatin in inflammatory bowel disease |
| title_short | Somatostatin in inflammatory bowel disease |
| title_sort | somatostatin in inflammatory bowel disease |
| url | http://dx.doi.org/10.1080/09629359791424 |
| work_keys_str_mv | AT jdvanbergeijk somatostatinininflammatoryboweldisease AT jhpwilson somatostatinininflammatoryboweldisease |