The “Target Sign” in a 46-Year-Old Patient with COVID-19 Pneumonia

COVID-19 has various imaging manifestations, most commonly peripheral ground-glass opacities with a basilar posterior predominance. Less common imaging manifestations include consolidations, findings typical of organizing pneumonia, such as “halo” or a “reverse halo” sign, and vascular enlargement....

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Main Authors: Alexandra Pérez Pérez, Rahul Lazarus, Anju Dubey
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2021/9956927
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author Alexandra Pérez Pérez
Rahul Lazarus
Anju Dubey
author_facet Alexandra Pérez Pérez
Rahul Lazarus
Anju Dubey
author_sort Alexandra Pérez Pérez
collection DOAJ
description COVID-19 has various imaging manifestations, most commonly peripheral ground-glass opacities with a basilar posterior predominance. Less common imaging manifestations include consolidations, findings typical of organizing pneumonia, such as “halo” or a “reverse halo” sign, and vascular enlargement. Our case describes a “target sign” on CT, which is uncommon but is increasingly being recognized. The target sign consists of a central nodular opacity with surrounding ground-glass opacity, then a surrounding relatively lucent ring, and a more peripheral ring of consolidation or ground-glass opacification. This may be the sequela of focal vascular enlargement, endothelial injury, microangiopathy, and perivascular inflammation. The case described involves a 46-year-old male who presented with subjective fevers, nonproductive cough, and hypoxia, subsequently diagnosed with COVID-19. CT imaging performed as part of initial work-up revealed multifocal ground-glass opacities scattered throughout the lung parenchyma, as well as multiple target sign lesions. Although it is a rare finding, the target sign, when present, may suggest the diagnosis of COVID-19.
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spelling doaj-art-8c7e0fd6f75c4789b727670781eeb4a72025-02-03T05:49:28ZengWileyCase Reports in Radiology2090-68702021-01-01202110.1155/2021/9956927The “Target Sign” in a 46-Year-Old Patient with COVID-19 PneumoniaAlexandra Pérez Pérez0Rahul Lazarus1Anju Dubey2Department of RadiologySUNY Downstate Medical Center/Kings County HospitalSUNY Downstate Medical Center/Kings County HospitalCOVID-19 has various imaging manifestations, most commonly peripheral ground-glass opacities with a basilar posterior predominance. Less common imaging manifestations include consolidations, findings typical of organizing pneumonia, such as “halo” or a “reverse halo” sign, and vascular enlargement. Our case describes a “target sign” on CT, which is uncommon but is increasingly being recognized. The target sign consists of a central nodular opacity with surrounding ground-glass opacity, then a surrounding relatively lucent ring, and a more peripheral ring of consolidation or ground-glass opacification. This may be the sequela of focal vascular enlargement, endothelial injury, microangiopathy, and perivascular inflammation. The case described involves a 46-year-old male who presented with subjective fevers, nonproductive cough, and hypoxia, subsequently diagnosed with COVID-19. CT imaging performed as part of initial work-up revealed multifocal ground-glass opacities scattered throughout the lung parenchyma, as well as multiple target sign lesions. Although it is a rare finding, the target sign, when present, may suggest the diagnosis of COVID-19.http://dx.doi.org/10.1155/2021/9956927
spellingShingle Alexandra Pérez Pérez
Rahul Lazarus
Anju Dubey
The “Target Sign” in a 46-Year-Old Patient with COVID-19 Pneumonia
Case Reports in Radiology
title The “Target Sign” in a 46-Year-Old Patient with COVID-19 Pneumonia
title_full The “Target Sign” in a 46-Year-Old Patient with COVID-19 Pneumonia
title_fullStr The “Target Sign” in a 46-Year-Old Patient with COVID-19 Pneumonia
title_full_unstemmed The “Target Sign” in a 46-Year-Old Patient with COVID-19 Pneumonia
title_short The “Target Sign” in a 46-Year-Old Patient with COVID-19 Pneumonia
title_sort target sign in a 46 year old patient with covid 19 pneumonia
url http://dx.doi.org/10.1155/2021/9956927
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