Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway
Uric acid is an effective antioxidant. Oxidized low-density lipoprotein (ox-LDL) is derived from circulating LDL and promotes atherosclerosis. The Keap1-Nrf2-ARE pathway is a key body pathway involved in protection against internal and external oxidative damages. The role of uric acid on vascular en...
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Main Authors: | Yajuan Lin, Yunpeng Xie, Zhujing Hao, Hailian Bi, Yang Liu, Xiaolei Yang, Yunlong Xia |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2021/5151168 |
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