An mpox quadrivalent mRNA vaccine elicits sustained and protective immunity in mice against lethal vaccinia virus challenge

An mpox quadrivalent mRNA vaccine elicits sustained and protective immunity in mice against lethal vaccinia virus challenge

Assessing the long-term efficacy of MPXV vaccine candidates is crucial for the global response to the ongoing mpox epidemic. Built upon our previous study of the mpox quadrivalent mRNA vaccine, herein we reported that MPXV-1103 could elicit sustained humoral and cellular immunity in mice, including...

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Main Authors: Entao Li, Qiyuan Yang, Wenyu Xie, Qizan Gong, Xiaoping Guo, Jinge Zhou, Jiachen Zhang, Xia Chuai, Yucai Wang, Sandra Chiu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2447619
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