Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients
Stem cells as a therapeutic measure for the treatment of different diseases have a great potential to give rise to different mature cells as they could be used to treat HIV-1 patients when provided with the convenient factors. Thus, this paper proposes a new mathematical model, represented by a syst...
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Format: | Article |
Language: | English |
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Wiley
2019-01-01
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Series: | Discrete Dynamics in Nature and Society |
Online Access: | http://dx.doi.org/10.1155/2019/6379142 |
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author | Manar A. Al Qudah Sana’a A. Zarea Saoussan A. Kallel-Jallouli |
author_facet | Manar A. Al Qudah Sana’a A. Zarea Saoussan A. Kallel-Jallouli |
author_sort | Manar A. Al Qudah |
collection | DOAJ |
description | Stem cells as a therapeutic measure for the treatment of different diseases have a great potential to give rise to different mature cells as they could be used to treat HIV-1 patients when provided with the convenient factors. Thus, this paper proposes a new mathematical model, represented by a system of ODEs, to study the effect of stem cell transplantation for HIV-1 patients. Since stem cells lineage passes through many stages to become more specialized cell types, investigating (theorizing) the best stage for these cells to be engrafted was needed. The proposed system of ODEs can help medicine make the right decision about the proposed therapy. |
format | Article |
id | doaj-art-8b9fa76925c747aa866329edf3ab1aa3 |
institution | Kabale University |
issn | 1026-0226 1607-887X |
language | English |
publishDate | 2019-01-01 |
publisher | Wiley |
record_format | Article |
series | Discrete Dynamics in Nature and Society |
spelling | doaj-art-8b9fa76925c747aa866329edf3ab1aa32025-02-03T06:13:08ZengWileyDiscrete Dynamics in Nature and Society1026-02261607-887X2019-01-01201910.1155/2019/63791426379142Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 PatientsManar A. Al Qudah0Sana’a A. Zarea1Saoussan A. Kallel-Jallouli2Mathematical Science Department, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaMathematical Science Department, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaUniversité de Tunis El Manar, LR03ES04, Faculté des Sciences de Tunis, 2092, Tunis, TunisiaStem cells as a therapeutic measure for the treatment of different diseases have a great potential to give rise to different mature cells as they could be used to treat HIV-1 patients when provided with the convenient factors. Thus, this paper proposes a new mathematical model, represented by a system of ODEs, to study the effect of stem cell transplantation for HIV-1 patients. Since stem cells lineage passes through many stages to become more specialized cell types, investigating (theorizing) the best stage for these cells to be engrafted was needed. The proposed system of ODEs can help medicine make the right decision about the proposed therapy.http://dx.doi.org/10.1155/2019/6379142 |
spellingShingle | Manar A. Al Qudah Sana’a A. Zarea Saoussan A. Kallel-Jallouli Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients Discrete Dynamics in Nature and Society |
title | Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients |
title_full | Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients |
title_fullStr | Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients |
title_full_unstemmed | Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients |
title_short | Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients |
title_sort | mathematical modeling to study multistage stem cell transplantation in hiv 1 patients |
url | http://dx.doi.org/10.1155/2019/6379142 |
work_keys_str_mv | AT manaraalqudah mathematicalmodelingtostudymultistagestemcelltransplantationinhiv1patients AT sanaaazarea mathematicalmodelingtostudymultistagestemcelltransplantationinhiv1patients AT saoussanakalleljallouli mathematicalmodelingtostudymultistagestemcelltransplantationinhiv1patients |