Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients

Stem cells as a therapeutic measure for the treatment of different diseases have a great potential to give rise to different mature cells as they could be used to treat HIV-1 patients when provided with the convenient factors. Thus, this paper proposes a new mathematical model, represented by a syst...

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Main Authors: Manar A. Al Qudah, Sana’a A. Zarea, Saoussan A. Kallel-Jallouli
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Discrete Dynamics in Nature and Society
Online Access:http://dx.doi.org/10.1155/2019/6379142
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author Manar A. Al Qudah
Sana’a A. Zarea
Saoussan A. Kallel-Jallouli
author_facet Manar A. Al Qudah
Sana’a A. Zarea
Saoussan A. Kallel-Jallouli
author_sort Manar A. Al Qudah
collection DOAJ
description Stem cells as a therapeutic measure for the treatment of different diseases have a great potential to give rise to different mature cells as they could be used to treat HIV-1 patients when provided with the convenient factors. Thus, this paper proposes a new mathematical model, represented by a system of ODEs, to study the effect of stem cell transplantation for HIV-1 patients. Since stem cells lineage passes through many stages to become more specialized cell types, investigating (theorizing) the best stage for these cells to be engrafted was needed. The proposed system of ODEs can help medicine make the right decision about the proposed therapy.
format Article
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institution Kabale University
issn 1026-0226
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language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Discrete Dynamics in Nature and Society
spelling doaj-art-8b9fa76925c747aa866329edf3ab1aa32025-02-03T06:13:08ZengWileyDiscrete Dynamics in Nature and Society1026-02261607-887X2019-01-01201910.1155/2019/63791426379142Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 PatientsManar A. Al Qudah0Sana’a A. Zarea1Saoussan A. Kallel-Jallouli2Mathematical Science Department, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaMathematical Science Department, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaUniversité de Tunis El Manar, LR03ES04, Faculté des Sciences de Tunis, 2092, Tunis, TunisiaStem cells as a therapeutic measure for the treatment of different diseases have a great potential to give rise to different mature cells as they could be used to treat HIV-1 patients when provided with the convenient factors. Thus, this paper proposes a new mathematical model, represented by a system of ODEs, to study the effect of stem cell transplantation for HIV-1 patients. Since stem cells lineage passes through many stages to become more specialized cell types, investigating (theorizing) the best stage for these cells to be engrafted was needed. The proposed system of ODEs can help medicine make the right decision about the proposed therapy.http://dx.doi.org/10.1155/2019/6379142
spellingShingle Manar A. Al Qudah
Sana’a A. Zarea
Saoussan A. Kallel-Jallouli
Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients
Discrete Dynamics in Nature and Society
title Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients
title_full Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients
title_fullStr Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients
title_full_unstemmed Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients
title_short Mathematical Modeling to Study Multistage Stem Cell Transplantation in HIV-1 Patients
title_sort mathematical modeling to study multistage stem cell transplantation in hiv 1 patients
url http://dx.doi.org/10.1155/2019/6379142
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