Mean Platelet Volume in Patients with Obstructive Sleep Apnea and Its Relationship with Simpler Heart Rate Derivatives
Some studies show increased mean platelet volume (MPV) in obstructive sleep apnea (OSA). The aim of this study was to evaluate MPV in OSA patients without cardiovascular risk factors and the possible association of heart rate derivatives with MPV. A total of 82 patients (aged 30–70 years) were divid...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2014/454701 |
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| author | Aydın Akyüz Dursun Çayan Akkoyun Mustafa Oran Hasan Değirmenci Recep Alp |
| author_facet | Aydın Akyüz Dursun Çayan Akkoyun Mustafa Oran Hasan Değirmenci Recep Alp |
| author_sort | Aydın Akyüz |
| collection | DOAJ |
| description | Some studies show increased mean platelet volume (MPV) in obstructive sleep apnea (OSA). The aim of this study was to evaluate MPV in OSA patients without cardiovascular risk factors and the possible association of heart rate derivatives with MPV. A total of 82 patients (aged 30–70 years) were divided into 2 groups according to the presence of either OSA or non-OSA as the control group. The OSA group consisted of 52 patients and the control group consisted of 30 subjects. Neither group was significantly different in terms of MPV values as well as heart rate (HR) derivatives such as minimum HR, maximum HR, the difference between maximum HR and minimum HR, mean HR, and heart rate performance index (HRPI) [(HR max. − HR min.)/HR mean] (P > 0.05 for all variables). In multivariate analysis, platelet count and percentages of recording time spent at arterial oxygen saturation < 90% significant variables are associated with MPV (β±SE: −0.004 ± 0.002, 95% CI, −0.008 to −0.001; P = 0.034) and (β±SE: 2.93 ± 1.93, 95% CI, 0.167 to 5.69; P = 0.038). Consequently, our findings predominantly suggest that there is a casual and reciprocal interaction between MPV and autonomic activation. |
| format | Article |
| id | doaj-art-8b9f0d0c696d4adfb1e54c545da63f19 |
| institution | Kabale University |
| issn | 2090-8016 2090-0597 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-8b9f0d0c696d4adfb1e54c545da63f192025-08-20T03:37:41ZengWileyCardiology Research and Practice2090-80162090-05972014-01-01201410.1155/2014/454701454701Mean Platelet Volume in Patients with Obstructive Sleep Apnea and Its Relationship with Simpler Heart Rate DerivativesAydın Akyüz0Dursun Çayan Akkoyun1Mustafa Oran2Hasan Değirmenci3Recep Alp4Department of Cardiology, Faculty of Medicine, Namık Kemal University, 59100 Tekirdağ, TurkeyDepartment of Cardiology, Faculty of Medicine, Namık Kemal University, 59100 Tekirdağ, TurkeyDepartment of Internal Medicine, Faculty of Medicine, Namık Kemal University, 59100 Tekirdağ, TurkeyDepartment of Cardiology, Faculty of Medicine, Namık Kemal University, 59100 Tekirdağ, TurkeyDepartment of Neurology, Faculty of Medicine, Namık Kemal University, 59100 Tekirdağ, TurkeySome studies show increased mean platelet volume (MPV) in obstructive sleep apnea (OSA). The aim of this study was to evaluate MPV in OSA patients without cardiovascular risk factors and the possible association of heart rate derivatives with MPV. A total of 82 patients (aged 30–70 years) were divided into 2 groups according to the presence of either OSA or non-OSA as the control group. The OSA group consisted of 52 patients and the control group consisted of 30 subjects. Neither group was significantly different in terms of MPV values as well as heart rate (HR) derivatives such as minimum HR, maximum HR, the difference between maximum HR and minimum HR, mean HR, and heart rate performance index (HRPI) [(HR max. − HR min.)/HR mean] (P > 0.05 for all variables). In multivariate analysis, platelet count and percentages of recording time spent at arterial oxygen saturation < 90% significant variables are associated with MPV (β±SE: −0.004 ± 0.002, 95% CI, −0.008 to −0.001; P = 0.034) and (β±SE: 2.93 ± 1.93, 95% CI, 0.167 to 5.69; P = 0.038). Consequently, our findings predominantly suggest that there is a casual and reciprocal interaction between MPV and autonomic activation.http://dx.doi.org/10.1155/2014/454701 |
| spellingShingle | Aydın Akyüz Dursun Çayan Akkoyun Mustafa Oran Hasan Değirmenci Recep Alp Mean Platelet Volume in Patients with Obstructive Sleep Apnea and Its Relationship with Simpler Heart Rate Derivatives Cardiology Research and Practice |
| title | Mean Platelet Volume in Patients with Obstructive Sleep Apnea and Its Relationship with Simpler Heart Rate Derivatives |
| title_full | Mean Platelet Volume in Patients with Obstructive Sleep Apnea and Its Relationship with Simpler Heart Rate Derivatives |
| title_fullStr | Mean Platelet Volume in Patients with Obstructive Sleep Apnea and Its Relationship with Simpler Heart Rate Derivatives |
| title_full_unstemmed | Mean Platelet Volume in Patients with Obstructive Sleep Apnea and Its Relationship with Simpler Heart Rate Derivatives |
| title_short | Mean Platelet Volume in Patients with Obstructive Sleep Apnea and Its Relationship with Simpler Heart Rate Derivatives |
| title_sort | mean platelet volume in patients with obstructive sleep apnea and its relationship with simpler heart rate derivatives |
| url | http://dx.doi.org/10.1155/2014/454701 |
| work_keys_str_mv | AT aydınakyuz meanplateletvolumeinpatientswithobstructivesleepapneaanditsrelationshipwithsimplerheartratederivatives AT dursuncayanakkoyun meanplateletvolumeinpatientswithobstructivesleepapneaanditsrelationshipwithsimplerheartratederivatives AT mustafaoran meanplateletvolumeinpatientswithobstructivesleepapneaanditsrelationshipwithsimplerheartratederivatives AT hasandegirmenci meanplateletvolumeinpatientswithobstructivesleepapneaanditsrelationshipwithsimplerheartratederivatives AT recepalp meanplateletvolumeinpatientswithobstructivesleepapneaanditsrelationshipwithsimplerheartratederivatives |