Systemic Treatment of Vitreous Inflammation
Non infectious vitreous inflammation is often vision threatening and can be associated with potentially life-threatening systemic conditions. Treatment is often challenging as it involves systemic medications that can be associated with adverse effects. The classes of drugs are ever expanding and in...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2012/936721 |
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| _version_ | 1832545655107616768 |
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| author | John B. Christoforidis Susie Chang Angela Jiang Jillian Wang Colleen M. Cebulla |
| author_facet | John B. Christoforidis Susie Chang Angela Jiang Jillian Wang Colleen M. Cebulla |
| author_sort | John B. Christoforidis |
| collection | DOAJ |
| description | Non infectious vitreous inflammation is often vision threatening and can be associated with potentially life-threatening systemic conditions. Treatment is often challenging as it involves systemic medications that can be associated with adverse effects. The classes of drugs are ever expanding and include corticosteroids, antimetabolites, alkylating agents, T-cell and calcineurin agents, biologic agents, and interferons. Each class of systemic therapy for non-infectious vitreous inflammation is reviewed. We discuss the mechanisms of action, usual clinical dosages, the specific conditions that are treated, the adverse effects, and usual course of treatment for each class of therapy. |
| format | Article |
| id | doaj-art-8b9d085070b24cedac119100379a43a3 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-8b9d085070b24cedac119100379a43a32025-02-03T07:25:08ZengWileyMediators of Inflammation0962-93511466-18612012-01-01201210.1155/2012/936721936721Systemic Treatment of Vitreous InflammationJohn B. Christoforidis0Susie Chang1Angela Jiang2Jillian Wang3Colleen M. Cebulla4Retina Division, Department of Ophthalmology, Wexner Medical Center at The Ohio State University, 915 Olentangy River Road, Suite 5000, Columbus, OH 43212, USARetina Division, Department of Ophthalmology, Wexner Medical Center at The Ohio State University, 915 Olentangy River Road, Suite 5000, Columbus, OH 43212, USARetina Division, Department of Ophthalmology, Wexner Medical Center at The Ohio State University, 915 Olentangy River Road, Suite 5000, Columbus, OH 43212, USARetina Division, Department of Ophthalmology, Wexner Medical Center at The Ohio State University, 915 Olentangy River Road, Suite 5000, Columbus, OH 43212, USARetina Division, Department of Ophthalmology, Wexner Medical Center at The Ohio State University, 915 Olentangy River Road, Suite 5000, Columbus, OH 43212, USANon infectious vitreous inflammation is often vision threatening and can be associated with potentially life-threatening systemic conditions. Treatment is often challenging as it involves systemic medications that can be associated with adverse effects. The classes of drugs are ever expanding and include corticosteroids, antimetabolites, alkylating agents, T-cell and calcineurin agents, biologic agents, and interferons. Each class of systemic therapy for non-infectious vitreous inflammation is reviewed. We discuss the mechanisms of action, usual clinical dosages, the specific conditions that are treated, the adverse effects, and usual course of treatment for each class of therapy.http://dx.doi.org/10.1155/2012/936721 |
| spellingShingle | John B. Christoforidis Susie Chang Angela Jiang Jillian Wang Colleen M. Cebulla Systemic Treatment of Vitreous Inflammation Mediators of Inflammation |
| title | Systemic Treatment of Vitreous Inflammation |
| title_full | Systemic Treatment of Vitreous Inflammation |
| title_fullStr | Systemic Treatment of Vitreous Inflammation |
| title_full_unstemmed | Systemic Treatment of Vitreous Inflammation |
| title_short | Systemic Treatment of Vitreous Inflammation |
| title_sort | systemic treatment of vitreous inflammation |
| url | http://dx.doi.org/10.1155/2012/936721 |
| work_keys_str_mv | AT johnbchristoforidis systemictreatmentofvitreousinflammation AT susiechang systemictreatmentofvitreousinflammation AT angelajiang systemictreatmentofvitreousinflammation AT jillianwang systemictreatmentofvitreousinflammation AT colleenmcebulla systemictreatmentofvitreousinflammation |