Anesthetic management of folders with severe kyphosis in ankylosing spondylitis: a single-center retrospective case series study

BackgroundAnkylosing spondylitis (AS) is a progressive inflammatory disease causing severe kyphosis, which complicates surgical management and increases complication risks. This study aims to analyze the characteristics of severe kyphosis in AS and explore methods to optimize perioperative managemen...

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Main Authors: Lin Peng, Qiang Li, Lingxi Zheng, Deng Zhao, Qiang Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1503912/full
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author Lin Peng
Qiang Li
Lingxi Zheng
Deng Zhao
Qiang Fu
Qiang Fu
author_facet Lin Peng
Qiang Li
Lingxi Zheng
Deng Zhao
Qiang Fu
Qiang Fu
author_sort Lin Peng
collection DOAJ
description BackgroundAnkylosing spondylitis (AS) is a progressive inflammatory disease causing severe kyphosis, which complicates surgical management and increases complication risks. This study aims to analyze the characteristics of severe kyphosis in AS and explore methods to optimize perioperative management and reduce complications.MethodsWe conducted a retrospective analysis of clinical data from five patients with severe kyphosis in AS who underwent surgery between October 2017 and February 2022. The patients had a mean age of 40.20 ± 8.50 years. The analysis included pathophysiological changes in folded patients and perioperative multidisciplinary intervention guidance. It also covered strict preoperative anesthetic evaluations, establishing an optimal fluid pathway during surgery, precise anesthetic monitoring and management, and applying postoperative multimodal analgesia and rehabilitation exercises to optimize perioperative anesthetic management.ResultsPreoperative cardiopulmonary function exercises were required to ensure patients could withstand surgery and anesthesia. Awake fiberoptic tracheal intubation was used to ensure airway safety and anesthesia. Hemodynamic evaluation and management were conducted using PICCO monitoring. Somatosensory evoked potentials (SSEP) and myogenic motor evoked potentials (MMEP) were utilized for neural axis monitoring. Hypothermia was designed to protect the spinal cord. To prevent massive blood loss, controlled hypotension and autotransfusion were implemented.ConclusionThe correction operation of severe spinal kyphosis is complex and requires a detailed anesthesia plan. Optimizing the management of difficult airways and respiratory regulation, guiding circulation and fluid management through comprehensive monitoring, avoiding factors that aggravate complications, improving postoperative analgesia, and encouraging active rehabilitation exercises are crucial goals for perioperative anesthesia management.
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spelling doaj-art-8b67340f102f400a8a3ab4d0ed3dd3312025-08-20T03:10:25ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-04-011210.3389/fmed.2025.15039121503912Anesthetic management of folders with severe kyphosis in ankylosing spondylitis: a single-center retrospective case series studyLin Peng0Qiang Li1Lingxi Zheng2Deng Zhao3Qiang Fu4Qiang Fu5Department of Anesthesiology, The Third People’s Hospital of Chengdu (The Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, ChinaDepartment of Anesthesiology, The Third People’s Hospital of Chengdu, Southwest Jiao Tong University, Chengdu, ChinaDepartment of Anesthesiology, The Third People’s Hospital of Chengdu (The Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, ChinaDepartment of Orthopaedics, The Third People’s Hospital of Chengdu, Southwest Jiao Tong University, Chengdu, ChinaDepartment of Anesthesiology, The Third People’s Hospital of Chengdu (The Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, ChinaDepartment of Anesthesiology, The Third People’s Hospital of Chengdu, Southwest Jiao Tong University, Chengdu, ChinaBackgroundAnkylosing spondylitis (AS) is a progressive inflammatory disease causing severe kyphosis, which complicates surgical management and increases complication risks. This study aims to analyze the characteristics of severe kyphosis in AS and explore methods to optimize perioperative management and reduce complications.MethodsWe conducted a retrospective analysis of clinical data from five patients with severe kyphosis in AS who underwent surgery between October 2017 and February 2022. The patients had a mean age of 40.20 ± 8.50 years. The analysis included pathophysiological changes in folded patients and perioperative multidisciplinary intervention guidance. It also covered strict preoperative anesthetic evaluations, establishing an optimal fluid pathway during surgery, precise anesthetic monitoring and management, and applying postoperative multimodal analgesia and rehabilitation exercises to optimize perioperative anesthetic management.ResultsPreoperative cardiopulmonary function exercises were required to ensure patients could withstand surgery and anesthesia. Awake fiberoptic tracheal intubation was used to ensure airway safety and anesthesia. Hemodynamic evaluation and management were conducted using PICCO monitoring. Somatosensory evoked potentials (SSEP) and myogenic motor evoked potentials (MMEP) were utilized for neural axis monitoring. Hypothermia was designed to protect the spinal cord. To prevent massive blood loss, controlled hypotension and autotransfusion were implemented.ConclusionThe correction operation of severe spinal kyphosis is complex and requires a detailed anesthesia plan. Optimizing the management of difficult airways and respiratory regulation, guiding circulation and fluid management through comprehensive monitoring, avoiding factors that aggravate complications, improving postoperative analgesia, and encouraging active rehabilitation exercises are crucial goals for perioperative anesthesia management.https://www.frontiersin.org/articles/10.3389/fmed.2025.1503912/fullanesthetic managementankylosing spondylitiskyphosis surgerysevere kyphosishemodynamic monitoring
spellingShingle Lin Peng
Qiang Li
Lingxi Zheng
Deng Zhao
Qiang Fu
Qiang Fu
Anesthetic management of folders with severe kyphosis in ankylosing spondylitis: a single-center retrospective case series study
Frontiers in Medicine
anesthetic management
ankylosing spondylitis
kyphosis surgery
severe kyphosis
hemodynamic monitoring
title Anesthetic management of folders with severe kyphosis in ankylosing spondylitis: a single-center retrospective case series study
title_full Anesthetic management of folders with severe kyphosis in ankylosing spondylitis: a single-center retrospective case series study
title_fullStr Anesthetic management of folders with severe kyphosis in ankylosing spondylitis: a single-center retrospective case series study
title_full_unstemmed Anesthetic management of folders with severe kyphosis in ankylosing spondylitis: a single-center retrospective case series study
title_short Anesthetic management of folders with severe kyphosis in ankylosing spondylitis: a single-center retrospective case series study
title_sort anesthetic management of folders with severe kyphosis in ankylosing spondylitis a single center retrospective case series study
topic anesthetic management
ankylosing spondylitis
kyphosis surgery
severe kyphosis
hemodynamic monitoring
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1503912/full
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AT dengzhao anestheticmanagementoffolderswithseverekyphosisinankylosingspondylitisasinglecenterretrospectivecaseseriesstudy
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