Osseous Metaplasia in Castleman's Disease: A Case Report
Background. Castleman's disease is a benign lymphoproliferative disorder. The disease may be localized or multicentric. Three histologic variants are recognized: hyaline vascular, plasma cell, and mixed types. Case. A 20-year-old man presented with large left axillary mass. The histologic exami...
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Language: | English |
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2012-01-01
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Series: | Case Reports in Medicine |
Online Access: | http://dx.doi.org/10.1155/2012/674870 |
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author | Maral Mokhtari Perikala Vijayananda Kumar |
author_facet | Maral Mokhtari Perikala Vijayananda Kumar |
author_sort | Maral Mokhtari |
collection | DOAJ |
description | Background. Castleman's disease is a benign lymphoproliferative disorder. The disease may be localized or multicentric. Three histologic variants are recognized: hyaline vascular, plasma cell, and mixed types. Case. A 20-year-old man presented with large left axillary mass. The histologic examination of the resected mass showed follicular pattern with large nodules of mantle cells arranged concentrically around atrophic and vascularized germinal centers. There was also some benign-appearing bone trabeculae interspersed with lymphoid tissue. The diagnosis of Castleman's disease, hyaline-vascular type with osseous metaplasia, was made. |
format | Article |
id | doaj-art-8b5e1737ac3f420586ba61fad8be1375 |
institution | Kabale University |
issn | 1687-9627 1687-9635 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Medicine |
spelling | doaj-art-8b5e1737ac3f420586ba61fad8be13752025-02-03T06:15:13ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/674870674870Osseous Metaplasia in Castleman's Disease: A Case ReportMaral Mokhtari0Perikala Vijayananda Kumar1Pathology Department, Shiraz University of Medical Sciences, Shiraz 71348-53185, IranPathology Department, Shiraz University of Medical Sciences, Shiraz 71348-53185, IranBackground. Castleman's disease is a benign lymphoproliferative disorder. The disease may be localized or multicentric. Three histologic variants are recognized: hyaline vascular, plasma cell, and mixed types. Case. A 20-year-old man presented with large left axillary mass. The histologic examination of the resected mass showed follicular pattern with large nodules of mantle cells arranged concentrically around atrophic and vascularized germinal centers. There was also some benign-appearing bone trabeculae interspersed with lymphoid tissue. The diagnosis of Castleman's disease, hyaline-vascular type with osseous metaplasia, was made.http://dx.doi.org/10.1155/2012/674870 |
spellingShingle | Maral Mokhtari Perikala Vijayananda Kumar Osseous Metaplasia in Castleman's Disease: A Case Report Case Reports in Medicine |
title | Osseous Metaplasia in Castleman's Disease: A Case Report |
title_full | Osseous Metaplasia in Castleman's Disease: A Case Report |
title_fullStr | Osseous Metaplasia in Castleman's Disease: A Case Report |
title_full_unstemmed | Osseous Metaplasia in Castleman's Disease: A Case Report |
title_short | Osseous Metaplasia in Castleman's Disease: A Case Report |
title_sort | osseous metaplasia in castleman s disease a case report |
url | http://dx.doi.org/10.1155/2012/674870 |
work_keys_str_mv | AT maralmokhtari osseousmetaplasiaincastlemansdiseaseacasereport AT perikalavijayanandakumar osseousmetaplasiaincastlemansdiseaseacasereport |