Osseous Metaplasia in Castleman's Disease: A Case Report

Background. Castleman's disease is a benign lymphoproliferative disorder. The disease may be localized or multicentric. Three histologic variants are recognized: hyaline vascular, plasma cell, and mixed types. Case. A 20-year-old man presented with large left axillary mass. The histologic exami...

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Main Authors: Maral Mokhtari, Perikala Vijayananda Kumar
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/674870
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author Maral Mokhtari
Perikala Vijayananda Kumar
author_facet Maral Mokhtari
Perikala Vijayananda Kumar
author_sort Maral Mokhtari
collection DOAJ
description Background. Castleman's disease is a benign lymphoproliferative disorder. The disease may be localized or multicentric. Three histologic variants are recognized: hyaline vascular, plasma cell, and mixed types. Case. A 20-year-old man presented with large left axillary mass. The histologic examination of the resected mass showed follicular pattern with large nodules of mantle cells arranged concentrically around atrophic and vascularized germinal centers. There was also some benign-appearing bone trabeculae interspersed with lymphoid tissue. The diagnosis of Castleman's disease, hyaline-vascular type with osseous metaplasia, was made.
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institution Kabale University
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spelling doaj-art-8b5e1737ac3f420586ba61fad8be13752025-02-03T06:15:13ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/674870674870Osseous Metaplasia in Castleman's Disease: A Case ReportMaral Mokhtari0Perikala Vijayananda Kumar1Pathology Department, Shiraz University of Medical Sciences, Shiraz 71348-53185, IranPathology Department, Shiraz University of Medical Sciences, Shiraz 71348-53185, IranBackground. Castleman's disease is a benign lymphoproliferative disorder. The disease may be localized or multicentric. Three histologic variants are recognized: hyaline vascular, plasma cell, and mixed types. Case. A 20-year-old man presented with large left axillary mass. The histologic examination of the resected mass showed follicular pattern with large nodules of mantle cells arranged concentrically around atrophic and vascularized germinal centers. There was also some benign-appearing bone trabeculae interspersed with lymphoid tissue. The diagnosis of Castleman's disease, hyaline-vascular type with osseous metaplasia, was made.http://dx.doi.org/10.1155/2012/674870
spellingShingle Maral Mokhtari
Perikala Vijayananda Kumar
Osseous Metaplasia in Castleman's Disease: A Case Report
Case Reports in Medicine
title Osseous Metaplasia in Castleman's Disease: A Case Report
title_full Osseous Metaplasia in Castleman's Disease: A Case Report
title_fullStr Osseous Metaplasia in Castleman's Disease: A Case Report
title_full_unstemmed Osseous Metaplasia in Castleman's Disease: A Case Report
title_short Osseous Metaplasia in Castleman's Disease: A Case Report
title_sort osseous metaplasia in castleman s disease a case report
url http://dx.doi.org/10.1155/2012/674870
work_keys_str_mv AT maralmokhtari osseousmetaplasiaincastlemansdiseaseacasereport
AT perikalavijayanandakumar osseousmetaplasiaincastlemansdiseaseacasereport