Acute Glomerulonephritis in a Child with Chlamydia pneumoniae Infection: A Case Report

Background. Infectious diseases seem to be an important and independent risk factor for renal failure, but the underlying mechanism of renal involvement during some kinds of infectious diseases is still unclear, even if the literature data report immunomediated and/or autoimmune mechanisms to expla...

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Main Authors: Giovanna Vitaliti, Raffaele Falsaperla, Leandra Giunta, Giuseppina Spataro, Venerando Rapisarda, Mario Velardita, Giuseppe Nunnari, Piero Pavone
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/570921
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author Giovanna Vitaliti
Raffaele Falsaperla
Leandra Giunta
Giuseppina Spataro
Venerando Rapisarda
Mario Velardita
Giuseppe Nunnari
Piero Pavone
author_facet Giovanna Vitaliti
Raffaele Falsaperla
Leandra Giunta
Giuseppina Spataro
Venerando Rapisarda
Mario Velardita
Giuseppe Nunnari
Piero Pavone
author_sort Giovanna Vitaliti
collection DOAJ
description Background. Infectious diseases seem to be an important and independent risk factor for renal failure, but the underlying mechanism of renal involvement during some kinds of infectious diseases is still unclear, even if the literature data report immunomediated and/or autoimmune mechanisms to explain the pathogenic relationship between the two diseases. In paediatric patients, Chlamydia pneumoniae is a rare cause of renal complications and it may manifest in several ways, mainly involving the respiratory system, even if also renal and glomerulalr complications, have been described. Case Diagnosis/Treatment. Herein we report a case of a 3-year-old child who developed an acute glomerulonephritis that was chronologically, clinically, and biologically related to a previous Chlamydia pneumoniae infection. On our knowledge, in the literature it is the youngest patient with renal involvement during course of Chlamydia pneumoniae infection ever reported. Conclusions. The present case supports the hypothesis of a rather close causal relationship between this infective agent and renal and glomerular symptoms occurred in this child, during an acute episode of respiratory disease.
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publisher Wiley
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series Case Reports in Medicine
spelling doaj-art-8b5b0e2bce414831a6c1de8aecb2f3852025-02-03T05:51:05ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/570921570921Acute Glomerulonephritis in a Child with Chlamydia pneumoniae Infection: A Case ReportGiovanna Vitaliti0Raffaele Falsaperla1Leandra Giunta2Giuseppina Spataro3Venerando Rapisarda4Mario Velardita5Giuseppe Nunnari6Piero Pavone7Pediatric Acute and Emergency Operative Unit, Policlinico-Vittorio-Emanuele University Hospital, University of Catania, Via Plebiscito 628, 95100 Catania, ItalyPediatric Acute and Emergency Operative Unit, Policlinico-Vittorio-Emanuele University Hospital, University of Catania, Via Plebiscito 628, 95100 Catania, ItalyPediatric Acute and Emergency Operative Unit, Policlinico-Vittorio-Emanuele University Hospital, University of Catania, Via Plebiscito 628, 95100 Catania, ItalyPediatric Consultant of the Regional Institution, ASP3, 95100 Catania, ItalyDepartment of Internal Medicine and Systemic Diseases, Division of Medicine for Job, University of Catania, 95100 Catania, ItalyPediatric Operative Unit, Gravina and Santo Pietro of Caltagirone Hospital, 95100 Catania, ItalyDivision of Infectious Diseases, Thomas Jefferson University, Philadelphia, PA, USAPediatric Acute and Emergency Operative Unit, Policlinico-Vittorio-Emanuele University Hospital, University of Catania, Via Plebiscito 628, 95100 Catania, ItalyBackground. Infectious diseases seem to be an important and independent risk factor for renal failure, but the underlying mechanism of renal involvement during some kinds of infectious diseases is still unclear, even if the literature data report immunomediated and/or autoimmune mechanisms to explain the pathogenic relationship between the two diseases. In paediatric patients, Chlamydia pneumoniae is a rare cause of renal complications and it may manifest in several ways, mainly involving the respiratory system, even if also renal and glomerulalr complications, have been described. Case Diagnosis/Treatment. Herein we report a case of a 3-year-old child who developed an acute glomerulonephritis that was chronologically, clinically, and biologically related to a previous Chlamydia pneumoniae infection. On our knowledge, in the literature it is the youngest patient with renal involvement during course of Chlamydia pneumoniae infection ever reported. Conclusions. The present case supports the hypothesis of a rather close causal relationship between this infective agent and renal and glomerular symptoms occurred in this child, during an acute episode of respiratory disease.http://dx.doi.org/10.1155/2013/570921
spellingShingle Giovanna Vitaliti
Raffaele Falsaperla
Leandra Giunta
Giuseppina Spataro
Venerando Rapisarda
Mario Velardita
Giuseppe Nunnari
Piero Pavone
Acute Glomerulonephritis in a Child with Chlamydia pneumoniae Infection: A Case Report
Case Reports in Medicine
title Acute Glomerulonephritis in a Child with Chlamydia pneumoniae Infection: A Case Report
title_full Acute Glomerulonephritis in a Child with Chlamydia pneumoniae Infection: A Case Report
title_fullStr Acute Glomerulonephritis in a Child with Chlamydia pneumoniae Infection: A Case Report
title_full_unstemmed Acute Glomerulonephritis in a Child with Chlamydia pneumoniae Infection: A Case Report
title_short Acute Glomerulonephritis in a Child with Chlamydia pneumoniae Infection: A Case Report
title_sort acute glomerulonephritis in a child with chlamydia pneumoniae infection a case report
url http://dx.doi.org/10.1155/2013/570921
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