A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male
Mediastinal germ cell tumors are extragonadal germ cell tumors (EGGCTs) commonly seen in children and young adults. They are more common in men. Clinically they are classified as teratomas, seminomas, and nonseminomatous germ cell tumors. Primary mediastinal yolk sac neoplasm is an extremely rare tu...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/8961486 |
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| _version_ | 1832547446685696000 |
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| author | Sammy G. Nakhla Srinath Sundararajan |
| author_facet | Sammy G. Nakhla Srinath Sundararajan |
| author_sort | Sammy G. Nakhla |
| collection | DOAJ |
| description | Mediastinal germ cell tumors are extragonadal germ cell tumors (EGGCTs) commonly seen in children and young adults. They are more common in men. Clinically they are classified as teratomas, seminomas, and nonseminomatous germ cell tumors. Primary mediastinal yolk sac neoplasm is an extremely rare tumor. We present here a very rare case of primary yolk sac tumor of the anterior mediastinum in a 73-year-old male. Mediastinal germ cell tumors have a worse prognosis than gonadal germ cell tumors. Chemotherapy followed by adjuvant surgery improves overall response in EGGCTs. However, comorbidities can render treatment with chemotherapy and surgery challenging in elderly patients. |
| format | Article |
| id | doaj-art-8b3423fe958b4a968474c18d93f0bc07 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-8b3423fe958b4a968474c18d93f0bc072025-02-03T06:44:46ZengWileyCase Reports in Oncological Medicine2090-67062090-67142016-01-01201610.1155/2016/89614868961486A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult MaleSammy G. Nakhla0Srinath Sundararajan1Department of Medicine, Southern Arizona VA Health Care System, Tucson, AZ 85723, USADepartment of Hematology/Oncology, University of Arizona Cancer Center, Tucson, AZ 85724, USAMediastinal germ cell tumors are extragonadal germ cell tumors (EGGCTs) commonly seen in children and young adults. They are more common in men. Clinically they are classified as teratomas, seminomas, and nonseminomatous germ cell tumors. Primary mediastinal yolk sac neoplasm is an extremely rare tumor. We present here a very rare case of primary yolk sac tumor of the anterior mediastinum in a 73-year-old male. Mediastinal germ cell tumors have a worse prognosis than gonadal germ cell tumors. Chemotherapy followed by adjuvant surgery improves overall response in EGGCTs. However, comorbidities can render treatment with chemotherapy and surgery challenging in elderly patients.http://dx.doi.org/10.1155/2016/8961486 |
| spellingShingle | Sammy G. Nakhla Srinath Sundararajan A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male Case Reports in Oncological Medicine |
| title | A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male |
| title_full | A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male |
| title_fullStr | A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male |
| title_full_unstemmed | A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male |
| title_short | A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male |
| title_sort | rare case of primary anterior mediastinal yolk sac tumor in an elderly adult male |
| url | http://dx.doi.org/10.1155/2016/8961486 |
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