The Role of IL-37 as an Anti-Inflammatory Biomarker in some Iraqi Rheumatoid Arthritis Patients and Its Correlation with DAS28
Interleukin-37 (IL-37) is a new anti-inflammatory cytokine that inhibits immunological response and inflammation. The purpose of this study is to look into the role of IL-37 and if it correlates with disease activity in some Iraqi RA patients. The scope of the investigation comprised of 76 females...
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middle technical university
2022-11-01
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| Series: | Journal of Techniques |
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| Online Access: | https://journal.mtu.edu.iq/index.php/MTU/article/view/708 |
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| author | Sattar Brissm Hassan Hanaa N. Abdullah Khalied Yassen Zakair |
| author_facet | Sattar Brissm Hassan Hanaa N. Abdullah Khalied Yassen Zakair |
| author_sort | Sattar Brissm Hassan |
| collection | DOAJ |
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Interleukin-37 (IL-37) is a new anti-inflammatory cytokine that inhibits immunological response and inflammation. The purpose of this study is to look into the role of IL-37 and if it correlates with disease activity in some Iraqi RA patients. The scope of the investigation comprised of 76 females with RA who are aged in the range of (45.38 ±1.23 years) and 40 individuals in the control group with age of (46.48 ± 2.02years). When compared to controls, the level of serum IL-37 was shown to be considerably elevated in RA patients. (49.16 ± 3.25pg/ml vs. 32.04 ± 2.22pg/ml; p ≤ 0.05). However, the DAS28 score results showed a non-significant difference between the mild and severe rheumatoid arthritis patients. There was a positive association, statistically significant between the DAS28 score and anti-CCP Abs, RF. A positive correlation between DAS28 and ESR. While non-significantly correlated between DAS28 and CRP, IL-37.
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| format | Article |
| id | doaj-art-8b1cd984d2c547b2a8c1024d36b7205d |
| institution | Kabale University |
| issn | 1818-653X 2708-8383 |
| language | English |
| publishDate | 2022-11-01 |
| publisher | middle technical university |
| record_format | Article |
| series | Journal of Techniques |
| spelling | doaj-art-8b1cd984d2c547b2a8c1024d36b7205d2025-01-19T11:07:06Zengmiddle technical universityJournal of Techniques1818-653X2708-83832022-11-014Special Issue10.51173/jt.v4i33.708The Role of IL-37 as an Anti-Inflammatory Biomarker in some Iraqi Rheumatoid Arthritis Patients and Its Correlation with DAS28Sattar Brissm Hassan0Hanaa N. Abdullah1Khalied Yassen Zakair2Medical City, Ministry of Health, IraqCollege of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqMedical laboratory Techniques Department, Technical Institute / Kut, Middle Technical University, Baghdad, Iraq Interleukin-37 (IL-37) is a new anti-inflammatory cytokine that inhibits immunological response and inflammation. The purpose of this study is to look into the role of IL-37 and if it correlates with disease activity in some Iraqi RA patients. The scope of the investigation comprised of 76 females with RA who are aged in the range of (45.38 ±1.23 years) and 40 individuals in the control group with age of (46.48 ± 2.02years). When compared to controls, the level of serum IL-37 was shown to be considerably elevated in RA patients. (49.16 ± 3.25pg/ml vs. 32.04 ± 2.22pg/ml; p ≤ 0.05). However, the DAS28 score results showed a non-significant difference between the mild and severe rheumatoid arthritis patients. There was a positive association, statistically significant between the DAS28 score and anti-CCP Abs, RF. A positive correlation between DAS28 and ESR. While non-significantly correlated between DAS28 and CRP, IL-37. https://journal.mtu.edu.iq/index.php/MTU/article/view/708Rheumatoid arthritisAnti-CCPIL-37DAS28 |
| spellingShingle | Sattar Brissm Hassan Hanaa N. Abdullah Khalied Yassen Zakair The Role of IL-37 as an Anti-Inflammatory Biomarker in some Iraqi Rheumatoid Arthritis Patients and Its Correlation with DAS28 Journal of Techniques Rheumatoid arthritis Anti-CCP IL-37 DAS28 |
| title | The Role of IL-37 as an Anti-Inflammatory Biomarker in some Iraqi Rheumatoid Arthritis Patients and Its Correlation with DAS28 |
| title_full | The Role of IL-37 as an Anti-Inflammatory Biomarker in some Iraqi Rheumatoid Arthritis Patients and Its Correlation with DAS28 |
| title_fullStr | The Role of IL-37 as an Anti-Inflammatory Biomarker in some Iraqi Rheumatoid Arthritis Patients and Its Correlation with DAS28 |
| title_full_unstemmed | The Role of IL-37 as an Anti-Inflammatory Biomarker in some Iraqi Rheumatoid Arthritis Patients and Its Correlation with DAS28 |
| title_short | The Role of IL-37 as an Anti-Inflammatory Biomarker in some Iraqi Rheumatoid Arthritis Patients and Its Correlation with DAS28 |
| title_sort | role of il 37 as an anti inflammatory biomarker in some iraqi rheumatoid arthritis patients and its correlation with das28 |
| topic | Rheumatoid arthritis Anti-CCP IL-37 DAS28 |
| url | https://journal.mtu.edu.iq/index.php/MTU/article/view/708 |
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