COph100: A comprehensive fundus image registration dataset from infants constituting the “RIDIRP” database

Abstract Retinal image registration is vital for diagnostic therapeutic applications within the field of ophthalmology. Existing public datasets, focusing on adult retinal pathologies with high-quality images, have limited number of image pairs and neglect clinical challenges. To address this gap, w...

Full description

Saved in:
Bibliographic Details
Main Authors: Yan Hu, Mingdao Gong, Zhongxi Qiu, Jiabao Liu, Hongli Shen, Mingzhen Yuan, Xiaoqing Zhang, Heng Li, Hai Lu, Jiang Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-04426-w
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832594985787064320
author Yan Hu
Mingdao Gong
Zhongxi Qiu
Jiabao Liu
Hongli Shen
Mingzhen Yuan
Xiaoqing Zhang
Heng Li
Hai Lu
Jiang Liu
author_facet Yan Hu
Mingdao Gong
Zhongxi Qiu
Jiabao Liu
Hongli Shen
Mingzhen Yuan
Xiaoqing Zhang
Heng Li
Hai Lu
Jiang Liu
author_sort Yan Hu
collection DOAJ
description Abstract Retinal image registration is vital for diagnostic therapeutic applications within the field of ophthalmology. Existing public datasets, focusing on adult retinal pathologies with high-quality images, have limited number of image pairs and neglect clinical challenges. To address this gap, we introduce COph100, a novel and challenging dataset known as the Comprehensive Ophthalmology Retinal Image Registration dataset for infants with a wide range of image quality issues constituting the public “RIDIRP” database. COph100 consists of 100 eyes, each with 2 to 9 examination sessions, amounting to a total of 491 image pairs carefully selected from the publicly available dataset. We manually labeled the corresponding ground truth image points and provided automatic vessel segmentation masks for each image. We have assessed COph100 in terms of image quality and registration outcomes using state-of-the-art algorithms. This resource enables a robust comparison of retinal registration methodologies and aids in the analysis of disease progression in infants, thereby deepening our understanding of pediatric ophthalmic conditions.
format Article
id doaj-art-8b0b8ad8b85e47f5a7ffe87d5f459fc9
institution Kabale University
issn 2052-4463
language English
publishDate 2025-01-01
publisher Nature Portfolio
record_format Article
series Scientific Data
spelling doaj-art-8b0b8ad8b85e47f5a7ffe87d5f459fc92025-01-19T12:10:03ZengNature PortfolioScientific Data2052-44632025-01-0112111010.1038/s41597-025-04426-wCOph100: A comprehensive fundus image registration dataset from infants constituting the “RIDIRP” databaseYan Hu0Mingdao Gong1Zhongxi Qiu2Jiabao Liu3Hongli Shen4Mingzhen Yuan5Xiaoqing Zhang6Heng Li7Hai Lu8Jiang Liu9Research Institute of Trustworthy Autonomous Systems and Department of Computer Science and Engineering, Southern University of Science and TechnologyResearch Institute of Trustworthy Autonomous Systems and Department of Computer Science and Engineering, Southern University of Science and TechnologyResearch Institute of Trustworthy Autonomous Systems and Department of Computer Science and Engineering, Southern University of Science and TechnologyResearch Institute of Trustworthy Autonomous Systems and Department of Computer Science and Engineering, Southern University of Science and TechnologyResearch Institute of Trustworthy Autonomous Systems and Department of Computer Science and Engineering, Southern University of Science and TechnologyBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key LaboratoryCenter for High Performance Computing and Shenzhen Key Laboratory of Intelligent Bioinformatics, Shenzhen Institute of Advanced Technology, Chinese Academy of SciencesResearch Institute of Trustworthy Autonomous Systems and Department of Computer Science and Engineering, Southern University of Science and TechnologyBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key LaboratoryResearch Institute of Trustworthy Autonomous Systems and Department of Computer Science and Engineering, Southern University of Science and TechnologyAbstract Retinal image registration is vital for diagnostic therapeutic applications within the field of ophthalmology. Existing public datasets, focusing on adult retinal pathologies with high-quality images, have limited number of image pairs and neglect clinical challenges. To address this gap, we introduce COph100, a novel and challenging dataset known as the Comprehensive Ophthalmology Retinal Image Registration dataset for infants with a wide range of image quality issues constituting the public “RIDIRP” database. COph100 consists of 100 eyes, each with 2 to 9 examination sessions, amounting to a total of 491 image pairs carefully selected from the publicly available dataset. We manually labeled the corresponding ground truth image points and provided automatic vessel segmentation masks for each image. We have assessed COph100 in terms of image quality and registration outcomes using state-of-the-art algorithms. This resource enables a robust comparison of retinal registration methodologies and aids in the analysis of disease progression in infants, thereby deepening our understanding of pediatric ophthalmic conditions.https://doi.org/10.1038/s41597-025-04426-w
spellingShingle Yan Hu
Mingdao Gong
Zhongxi Qiu
Jiabao Liu
Hongli Shen
Mingzhen Yuan
Xiaoqing Zhang
Heng Li
Hai Lu
Jiang Liu
COph100: A comprehensive fundus image registration dataset from infants constituting the “RIDIRP” database
Scientific Data
title COph100: A comprehensive fundus image registration dataset from infants constituting the “RIDIRP” database
title_full COph100: A comprehensive fundus image registration dataset from infants constituting the “RIDIRP” database
title_fullStr COph100: A comprehensive fundus image registration dataset from infants constituting the “RIDIRP” database
title_full_unstemmed COph100: A comprehensive fundus image registration dataset from infants constituting the “RIDIRP” database
title_short COph100: A comprehensive fundus image registration dataset from infants constituting the “RIDIRP” database
title_sort coph100 a comprehensive fundus image registration dataset from infants constituting the ridirp database
url https://doi.org/10.1038/s41597-025-04426-w
work_keys_str_mv AT yanhu coph100acomprehensivefundusimageregistrationdatasetfrominfantsconstitutingtheridirpdatabase
AT mingdaogong coph100acomprehensivefundusimageregistrationdatasetfrominfantsconstitutingtheridirpdatabase
AT zhongxiqiu coph100acomprehensivefundusimageregistrationdatasetfrominfantsconstitutingtheridirpdatabase
AT jiabaoliu coph100acomprehensivefundusimageregistrationdatasetfrominfantsconstitutingtheridirpdatabase
AT honglishen coph100acomprehensivefundusimageregistrationdatasetfrominfantsconstitutingtheridirpdatabase
AT mingzhenyuan coph100acomprehensivefundusimageregistrationdatasetfrominfantsconstitutingtheridirpdatabase
AT xiaoqingzhang coph100acomprehensivefundusimageregistrationdatasetfrominfantsconstitutingtheridirpdatabase
AT hengli coph100acomprehensivefundusimageregistrationdatasetfrominfantsconstitutingtheridirpdatabase
AT hailu coph100acomprehensivefundusimageregistrationdatasetfrominfantsconstitutingtheridirpdatabase
AT jiangliu coph100acomprehensivefundusimageregistrationdatasetfrominfantsconstitutingtheridirpdatabase