The Infection Returns: A Case of Pulmonary Sporotrichosis Relapse after Chemotherapy

Background. Pulmonary sporotrichosis is a rare disease caused by a dimorphic fungus, Sporothrix schenckii. It is rarely found in association with malignancy. We present a case of pulmonary sporotrichosis recurrence after chemotherapy. Case Presentation. A 44-year-old man, treated for pulmonary sporo...

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Main Authors: Samid M. Farooqui, Houssein Youness
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2018/1384029
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author Samid M. Farooqui
Houssein Youness
author_facet Samid M. Farooqui
Houssein Youness
author_sort Samid M. Farooqui
collection DOAJ
description Background. Pulmonary sporotrichosis is a rare disease caused by a dimorphic fungus, Sporothrix schenckii. It is rarely found in association with malignancy. We present a case of pulmonary sporotrichosis recurrence after chemotherapy. Case Presentation. A 44-year-old man, treated for pulmonary sporotrichosis in the past, presented with dysphagia and was found to have squamous cell carcinoma of the esophagus. After undergoing chemotherapy, extensive cavitary lesions were observed on thoracic computed tomography scan. A bronchoalveolar lavage revealed the presence of Sporothrix schenckii sensu lato. Despite treatment with itraconazole, he eventually required a left pneumonectomy for progressive destructive cavitary lesions involving the left lung. Conclusion. This case highlights the importance of considering past fungal infections, albeit cured, in patients initiating immunosuppressive therapy.
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spelling doaj-art-8affba0c7d7c4869beb6bf0c22c7c9862025-02-03T05:45:01ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/13840291384029The Infection Returns: A Case of Pulmonary Sporotrichosis Relapse after ChemotherapySamid M. Farooqui0Houssein Youness1Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USASection of Pulmonary, Critical Care, and Sleep Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USABackground. Pulmonary sporotrichosis is a rare disease caused by a dimorphic fungus, Sporothrix schenckii. It is rarely found in association with malignancy. We present a case of pulmonary sporotrichosis recurrence after chemotherapy. Case Presentation. A 44-year-old man, treated for pulmonary sporotrichosis in the past, presented with dysphagia and was found to have squamous cell carcinoma of the esophagus. After undergoing chemotherapy, extensive cavitary lesions were observed on thoracic computed tomography scan. A bronchoalveolar lavage revealed the presence of Sporothrix schenckii sensu lato. Despite treatment with itraconazole, he eventually required a left pneumonectomy for progressive destructive cavitary lesions involving the left lung. Conclusion. This case highlights the importance of considering past fungal infections, albeit cured, in patients initiating immunosuppressive therapy.http://dx.doi.org/10.1155/2018/1384029
spellingShingle Samid M. Farooqui
Houssein Youness
The Infection Returns: A Case of Pulmonary Sporotrichosis Relapse after Chemotherapy
Case Reports in Medicine
title The Infection Returns: A Case of Pulmonary Sporotrichosis Relapse after Chemotherapy
title_full The Infection Returns: A Case of Pulmonary Sporotrichosis Relapse after Chemotherapy
title_fullStr The Infection Returns: A Case of Pulmonary Sporotrichosis Relapse after Chemotherapy
title_full_unstemmed The Infection Returns: A Case of Pulmonary Sporotrichosis Relapse after Chemotherapy
title_short The Infection Returns: A Case of Pulmonary Sporotrichosis Relapse after Chemotherapy
title_sort infection returns a case of pulmonary sporotrichosis relapse after chemotherapy
url http://dx.doi.org/10.1155/2018/1384029
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