The effect of non-opioid multimodal analgesics and dexamethasone monotherapy on acute incisional pain behaviors in rats

The use of non-opioid multimodal analgesics (NMA) may enhance pain relief and decrease opioid dependence in managing acute incisional pain, although this remains debated. A clinical trial found NMA ineffective compared to placebo, prompting us to investigate its impact on pain-like behaviors in anim...

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Bibliographic Details
Main Authors: Ratan K. Banik, Malcolm E. Johns, Twan Sia, Donald A. Simone
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pain Research
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2025.1569246/full
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