Influence of Inflammatory Cytokines IL-1β and IFNγ on Sarcoplasmic Aggregation of p62 and TDP-43 in Myotubes
Skeletal muscle of patients with sporadic inclusion body myositis (sIBM) presents with inflammation, including upregulation of inflammatory cytokines such as interferon γ (IFNγ). Non-inflammatory features are also observed, like the sarcoplasmic accumulation of proteins including TDP-43 and p62. Thi...
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Main Authors: | Bryony McCord, Richard M. Day |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2023/9018470 |
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