Neuroprotection effect of bovine umbilical mesenchymal stem cell-conditioned medium on the rat model of Alzheimer's disease mediated by upregulation of BDNF and NGF and downregulation of TNF-α and IL-1β

Neuroprotection effect of bovine umbilical mesenchymal stem cell-conditioned medium on the rat model of Alzheimer's disease mediated by upregulation of BDNF and NGF and downregulation of TNF-α and IL-1β

Background: Neurodegenerative diseases (NDD) are distinguished by impairment and depletion of nerve cells; one of the most common NDDs is Alzheimer's Disease (AD), which can appear in early onset or late onset. In recent years, the secretome or conditioned medium of mesenchymal stem cells...

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Bibliographic Details
Main Authors: Hevi Wihadmadyatami, Muhammad Ali Zulfikar, Herawati Herawati, Srikanth Karnati, Golda Rani Saragih, Dinda Aliffia, Dyah A.O.A. Pratama, Nurrahmi Handayani, Ulayatul Kustiati, Dewi Ratih Tirtosari, Yudy Tjahjono
Format: Article
Language:English
Published: Tripoli University 2025-01-01
Series:Open Veterinary Journal
Subjects:
alzheimer's disease
bumsc-cm
rat model
tnf-α
il-1β
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=213898
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