Evaluating anticancer activity of emodin by enhancing antioxidant activities and affecting PKC/ADAMTS4 pathway in thioacetamide-induced hepatocellular carcinoma in rats

Evaluating anticancer activity of emodin by enhancing antioxidant activities and affecting PKC/ADAMTS4 pathway in thioacetamide-induced hepatocellular carcinoma in rats

Emodin is a naturally occurring anthraquinone derivative with a wide range of pharmacological activities, including neuroprotective and anti-inflammatory activities. We aim to assess the anticancer activity of emodin against hepatocellular carcinoma (HCC) in rat models using the proliferation, invas...

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Bibliographic Details
Main Authors: Hanan M. Hassan, Ahmed M. Hamdan, Abdullah Alattar, Reem Alshaman, Omar Bahattab, Mohammed M. H. Al-Gayyar
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Redox Report
Subjects:
ADAMTS4
Aggrecan
Angiogenesis
emodin
hepatocellular carcinoma
PKCδ
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2024.2365590
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