A Case of Acute Psychosis in an Adolescent Male
Primary hyperparathyroidism (PHPT) is a disorder of calcium homeostasis. We report the case of a 17-year-old adolescent male, who presented with an acute psychosis coinciding with severe hypercalcemia and markedly elevated intact parathyroid hormone (iPTH) level and low vitamin D level. A Sestamibi...
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| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2014/937631 |
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| author | Ghufran Babar Ramin Alemzadeh |
| author_facet | Ghufran Babar Ramin Alemzadeh |
| author_sort | Ghufran Babar |
| collection | DOAJ |
| description | Primary hyperparathyroidism (PHPT) is a disorder of calcium homeostasis. We report the case of a 17-year-old adolescent male, who presented with an acute psychosis coinciding with severe hypercalcemia and markedly elevated intact parathyroid hormone (iPTH) level and low vitamin D level. A Sestamibi scan showed a positive signal inferior to the left lobe of the thyroid gland. He had only a partial response to the initial medical and psychiatric management. The enlarged parathyroid gland was resected surgically and postoperatively serum calcium and iPTH levels normalized. The histopathology was compatible with a benign adenoma. Patient’s acute psychotic symptoms resolved gradually after surgery; however he remained under psychiatric care for the behavioral issues for about 6 months after surgery. While psychosis is a rare clinical manifestation of hypercalcemia secondary to PHPT in pediatric population, it should be considered as a clinical clue in an otherwise asymptomatic pediatric patient. |
| format | Article |
| id | doaj-art-8ac4a507008b4b0181201fdaea74e6cd |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-8ac4a507008b4b0181201fdaea74e6cd2025-02-03T07:25:45ZengWileyCase Reports in Endocrinology2090-65012090-651X2014-01-01201410.1155/2014/937631937631A Case of Acute Psychosis in an Adolescent MaleGhufran Babar0Ramin Alemzadeh1Section of Pediatric Endocrinology, Children’s Mercy Hospitals and Clinics, 3101 Broadway Boulevard, Kansas City, MO 64111, USADivision of Pediatric Endocrinology, University of Illinois College of Medicine at Chicago, 1853 W. Polk Street, Chicago, IL 60612, USAPrimary hyperparathyroidism (PHPT) is a disorder of calcium homeostasis. We report the case of a 17-year-old adolescent male, who presented with an acute psychosis coinciding with severe hypercalcemia and markedly elevated intact parathyroid hormone (iPTH) level and low vitamin D level. A Sestamibi scan showed a positive signal inferior to the left lobe of the thyroid gland. He had only a partial response to the initial medical and psychiatric management. The enlarged parathyroid gland was resected surgically and postoperatively serum calcium and iPTH levels normalized. The histopathology was compatible with a benign adenoma. Patient’s acute psychotic symptoms resolved gradually after surgery; however he remained under psychiatric care for the behavioral issues for about 6 months after surgery. While psychosis is a rare clinical manifestation of hypercalcemia secondary to PHPT in pediatric population, it should be considered as a clinical clue in an otherwise asymptomatic pediatric patient.http://dx.doi.org/10.1155/2014/937631 |
| spellingShingle | Ghufran Babar Ramin Alemzadeh A Case of Acute Psychosis in an Adolescent Male Case Reports in Endocrinology |
| title | A Case of Acute Psychosis in an Adolescent Male |
| title_full | A Case of Acute Psychosis in an Adolescent Male |
| title_fullStr | A Case of Acute Psychosis in an Adolescent Male |
| title_full_unstemmed | A Case of Acute Psychosis in an Adolescent Male |
| title_short | A Case of Acute Psychosis in an Adolescent Male |
| title_sort | case of acute psychosis in an adolescent male |
| url | http://dx.doi.org/10.1155/2014/937631 |
| work_keys_str_mv | AT ghufranbabar acaseofacutepsychosisinanadolescentmale AT raminalemzadeh acaseofacutepsychosisinanadolescentmale AT ghufranbabar caseofacutepsychosisinanadolescentmale AT raminalemzadeh caseofacutepsychosisinanadolescentmale |