Suppressive Activity of a Macrolide Antibiotic, Roxithromycin, on Pro-Inflammatory Cytokine Production in Vitro and in Vivo

Suppressive Activity of a Macrolide Antibiotic, Roxithromycin, on Pro-Inflammatory Cytokine Production in Vitro and in Vivo

This study was designed to examine the influence of a macrolide antibiotic, roxithromycin (RXM), on the production of pro-inflammatory cytokines, interleukin (IL)-1β and tumor necrosis factor (TNF)-α. In the first experiments, we examined the effect of RXM on in vitro cytokine production from lipopo...

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Bibliographic Details
Main Authors: H. Suzaki, K. Asano, S. Ohki, K. Kanai, T. Mizutani, T. Hisamitsu
Format: Article
Language:English
Published: Wiley 1999-01-01
Series:Mediators of Inflammation
Subjects:
Roxithromycin
Interleukin-1β
Tumor necrosis factor-α
Inhibition
Mouse
In vivo
In vitro.
Online Access:http://dx.doi.org/10.1080/09629359990351
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http://dx.doi.org/10.1080/09629359990351

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