Lactobacillus rhamnosus GG as an Effective Probiotic for Murine Giardiasis
The gut microflora is an important constituent in the intestinal mucosal barrier and has been introduced as the concept of probiotic therapy that beneficially affects the host by improving its intestinal microbial balance. Therefore, the main objective of the study was to explore the protective pote...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Interdisciplinary Perspectives on Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2011/795219 |
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| author | Nisha Goyal Ram Prakash Tiwari Geeta Shukla |
| author_facet | Nisha Goyal Ram Prakash Tiwari Geeta Shukla |
| author_sort | Nisha Goyal |
| collection | DOAJ |
| description | The gut microflora is an important constituent in the intestinal mucosal barrier and has been introduced as the concept of probiotic therapy that beneficially affects the host by improving its intestinal microbial balance. Therefore, the main objective of the study was to explore the protective potential of various lactobacilli strains for murine giardiasis. By experimentation, it was found that the probiotic supplementation of either Lactobacillus casei, L. acidophilus, L. plantarum, or L. rhamnosus GG, 7 days prior to inoculation with G. lamblia trophozoites, reduced the rate of cyst excretion compared with Giardia-infected mice. Interestingly, L. GG was found to be the most effective probiotic in reducing the duration of giardia cycle and acts as an effective prophylactic probiotic for murine giardiasis but needs to be clinically correlated due to entirely different human microflora. |
| format | Article |
| id | doaj-art-8a9a105df2ae4d5e901eef02c0cdfc16 |
| institution | Kabale University |
| issn | 1687-708X 1687-7098 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Interdisciplinary Perspectives on Infectious Diseases |
| spelling | doaj-art-8a9a105df2ae4d5e901eef02c0cdfc162025-02-03T01:02:35ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-708X1687-70982011-01-01201110.1155/2011/795219795219Lactobacillus rhamnosus GG as an Effective Probiotic for Murine GiardiasisNisha Goyal0Ram Prakash Tiwari1Geeta Shukla2Department of Microbiology, Panjab University, Chandigarh 160014, IndiaDepartment of Microbiology, Panjab University, Chandigarh 160014, IndiaDepartment of Microbiology, Panjab University, Chandigarh 160014, IndiaThe gut microflora is an important constituent in the intestinal mucosal barrier and has been introduced as the concept of probiotic therapy that beneficially affects the host by improving its intestinal microbial balance. Therefore, the main objective of the study was to explore the protective potential of various lactobacilli strains for murine giardiasis. By experimentation, it was found that the probiotic supplementation of either Lactobacillus casei, L. acidophilus, L. plantarum, or L. rhamnosus GG, 7 days prior to inoculation with G. lamblia trophozoites, reduced the rate of cyst excretion compared with Giardia-infected mice. Interestingly, L. GG was found to be the most effective probiotic in reducing the duration of giardia cycle and acts as an effective prophylactic probiotic for murine giardiasis but needs to be clinically correlated due to entirely different human microflora.http://dx.doi.org/10.1155/2011/795219 |
| spellingShingle | Nisha Goyal Ram Prakash Tiwari Geeta Shukla Lactobacillus rhamnosus GG as an Effective Probiotic for Murine Giardiasis Interdisciplinary Perspectives on Infectious Diseases |
| title | Lactobacillus rhamnosus GG as an Effective Probiotic for Murine Giardiasis |
| title_full | Lactobacillus rhamnosus GG as an Effective Probiotic for Murine Giardiasis |
| title_fullStr | Lactobacillus rhamnosus GG as an Effective Probiotic for Murine Giardiasis |
| title_full_unstemmed | Lactobacillus rhamnosus GG as an Effective Probiotic for Murine Giardiasis |
| title_short | Lactobacillus rhamnosus GG as an Effective Probiotic for Murine Giardiasis |
| title_sort | lactobacillus rhamnosus gg as an effective probiotic for murine giardiasis |
| url | http://dx.doi.org/10.1155/2011/795219 |
| work_keys_str_mv | AT nishagoyal lactobacillusrhamnosusggasaneffectiveprobioticformurinegiardiasis AT ramprakashtiwari lactobacillusrhamnosusggasaneffectiveprobioticformurinegiardiasis AT geetashukla lactobacillusrhamnosusggasaneffectiveprobioticformurinegiardiasis |