In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa
In vitro synergy testing using levofloxacin (LVX) plus piperacillin/tazobactam (TZP) was performed by Etest and time-kill assay (TKA) for 31 unique fluoroquinolone-resistant Pseudomonas aeruginosa isolates. The Etest method showed synergy for 9/31 (29%) of isolates, while TKA showed synergy with 14/...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Interdisciplinary Perspectives on Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2009/984934 |
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| _version_ | 1832558739290324992 |
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| author | Vladimir Chachanidze Aixa Curbelo-Irizarry Deborah Ashcraft George Pankey |
| author_facet | Vladimir Chachanidze Aixa Curbelo-Irizarry Deborah Ashcraft George Pankey |
| author_sort | Vladimir Chachanidze |
| collection | DOAJ |
| description | In vitro synergy testing using levofloxacin (LVX) plus piperacillin/tazobactam (TZP) was performed by Etest and time-kill assay (TKA) for 31 unique fluoroquinolone-resistant Pseudomonas aeruginosa isolates. The Etest method showed synergy for 9/31 (29%) of isolates, while TKA showed synergy with 14/31 (45%) of isolates. When comparing the Etest method and TKA, concordant results for synergy, antagonism, and indifference were obtained for 24/31 (77%) of the isolates tested. |
| format | Article |
| id | doaj-art-8a95506ceacd417d94e9566fb23fd049 |
| institution | Kabale University |
| issn | 1687-708X 1687-7098 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Interdisciplinary Perspectives on Infectious Diseases |
| spelling | doaj-art-8a95506ceacd417d94e9566fb23fd0492025-02-03T01:31:41ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-708X1687-70982009-01-01200910.1155/2009/984934984934In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosaVladimir Chachanidze0Aixa Curbelo-Irizarry1Deborah Ashcraft2George Pankey3Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USAPremier Infectious Disease Care, 320 Edinburgh Dr., Winter Park, FL 32792, USAOchsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USAOchsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USAIn vitro synergy testing using levofloxacin (LVX) plus piperacillin/tazobactam (TZP) was performed by Etest and time-kill assay (TKA) for 31 unique fluoroquinolone-resistant Pseudomonas aeruginosa isolates. The Etest method showed synergy for 9/31 (29%) of isolates, while TKA showed synergy with 14/31 (45%) of isolates. When comparing the Etest method and TKA, concordant results for synergy, antagonism, and indifference were obtained for 24/31 (77%) of the isolates tested.http://dx.doi.org/10.1155/2009/984934 |
| spellingShingle | Vladimir Chachanidze Aixa Curbelo-Irizarry Deborah Ashcraft George Pankey In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa Interdisciplinary Perspectives on Infectious Diseases |
| title | In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa |
| title_full | In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa |
| title_fullStr | In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa |
| title_full_unstemmed | In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa |
| title_short | In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa |
| title_sort | in vitro synergy of levofloxacin plus piperacillin tazobactam against pseudomonas aeruginosa |
| url | http://dx.doi.org/10.1155/2009/984934 |
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