Transcription factor 3 is dysregulated in megakaryocytes in myelofibrosis

Transcription factor 3 is dysregulated in megakaryocytes in myelofibrosis

Transcription factor 3 (TCF3) is a DNA transcription factor that modulates megakaryocyte development. Although abnormal TCF3 expression has been identified in a range of hematological malignancies, to date, it has not been investigated in myelofibrosis (MF). MF is a Philadelphia-negative myeloprolif...

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Bibliographic Details
Main Authors: Ryan J Collinson, Lynne Wilson, Darren Boey, Zi Yun Ng, Bob Mirzai, Hun S Chuah, Rebecca Howman, Carolyn S Grove, Jacques A J Malherbe, Michael F Leahy, Matthew D Linden, Kathryn A Fuller, Wendy N Erber, Belinda B Guo
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Platelets
Subjects:
Megakaryocyte
myelofibrosis
myeloproliferative neoplasms
next-generation sequencing
platelets
TCF3
Online Access:https://www.tandfonline.com/doi/10.1080/09537104.2024.2304173
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