Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase-B for the Treatment of Alzheimer’s Disease

Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase-B for the Treatment of Alzheimer’s Disease

Alzheimer’s disease (AD) is a multi-factorial neurodegenerative disease with a complex pathomechanism that can be best treated with multi-target medications. Among the possible molecular targets involved in AD, acetylcholinesterase (AChE) and monoamine oxidase B (MAO-B) are well recognized because t...

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Bibliographic Details
Main Authors: Ayesha Asim, Michał K. Jastrzębski, Agnieszka A. Kaczor
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
Subjects:
dual inhibitors
Acetylcholine Esterase (AChE)
Monoamine Oxidase-B (MAO-B)
molecular modeling
SAR
Online Access:https://www.mdpi.com/1420-3049/30/14/2975
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