Venous vessel-wall assessment with superb microvascular imaging in Behçet syndrome
Objectives Superb microvascular imaging (SMI) provides a more sensitive assessment of small vessels compared with power and colour Doppler ultrasonography (PDUS and CDUS). We aimed to investigate the potential of SMI for use in research and clinical practice in Behçet syndrome (BS) and to gain a bet...
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BMJ Publishing Group
2025-04-01
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| Series: | RMD Open |
| Online Access: | https://rmdopen.bmj.com/content/11/2/e005382.full |
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| author | Gulen Hatemi Yesim Ozguler Melike Melikoğlu Sinem Nihal Esatoglu İbrahim Adaletli Yasemin Kayadibi Ugur Kimyon Ayse Kalyoncu Ucar |
| author_facet | Gulen Hatemi Yesim Ozguler Melike Melikoğlu Sinem Nihal Esatoglu İbrahim Adaletli Yasemin Kayadibi Ugur Kimyon Ayse Kalyoncu Ucar |
| author_sort | Gulen Hatemi |
| collection | DOAJ |
| description | Objectives Superb microvascular imaging (SMI) provides a more sensitive assessment of small vessels compared with power and colour Doppler ultrasonography (PDUS and CDUS). We aimed to investigate the potential of SMI for use in research and clinical practice in Behçet syndrome (BS) and to gain a better understanding of erythema nodosum (EN) like and superficial thrombophlebitis (STM) lesions using SMI.Methods We studied 51 patients with BS and 31 patients with non-BS with red palpable lesions on physical examination. B-mode US, CDUS, PDUS and SMI were performed and recorded by the same radiologist and recorded images were additionally evaluated independently by another radiologist. Vessel-wall signal intensity of STM lesions by SMI was graded in four groups according to the percentages of the affected vessel-wall area (Grade 0: no signal, Grade 1: < 25%, Grade 2: 25%–50%, Grade 3: 50%–75% and Grade 4: >75%).Results The lesions of 26 patients with BS and 17 patients with non-BS were diagnosed as STM with CDUS. SMI of STM lesions revealed vessel-wall signals in 21/26 patients with BS (81%), in contrast to only 3/17 (18%) patients with non-BS. While 16 of 21 patients with BS (76%) had at least grade 2 signal, only 1 of 3 non-BS had it. Lesions of 25 BS and 11 non-BS were diagnosed as EN by CDUS and SMI showed no vessel-wall signal in these patients.Conclusions Evaluation of the vessel wall with SMI in BS may be a promising approach for showing inflammation as an inexpensive, non-invasive and reliable imaging method that does not require a contrast agent. |
| format | Article |
| id | doaj-art-8a3ea8a71ccf488ab57cfd812f8a2021 |
| institution | DOAJ |
| issn | 2056-5933 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | RMD Open |
| spelling | doaj-art-8a3ea8a71ccf488ab57cfd812f8a20212025-08-20T03:15:03ZengBMJ Publishing GroupRMD Open2056-59332025-04-0111210.1136/rmdopen-2024-005382Venous vessel-wall assessment with superb microvascular imaging in Behçet syndromeGulen Hatemi0Yesim Ozguler1Melike Melikoğlu2Sinem Nihal Esatoglu3İbrahim Adaletli4Yasemin Kayadibi5Ugur Kimyon6Ayse Kalyoncu Ucar7Cerrahpasa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Istanbul, TurkeyCerrahpasa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Istanbul, TurkeyCerrahpasa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Istanbul, TurkeyCerrahpasa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Istanbul, TurkeyCerrahpasa Faculty of Medicine, Department of Internal Medicine, Division of Radiology, Istanbul University-Cerrahpasa, Istanbul, TurkeyCerrahpasa Faculty of Medicine, Department of Internal Medicine, Division of Radiology, Istanbul University-Cerrahpasa, Istanbul, TurkeyCerrahpasa Faculty of Medicine, Department of Internal Medicine, Istanbul University-Cerrahpasa, Istanbul, TurkeyCerrahpasa Faculty of Medicine, Department of Internal Medicine, Division of Radiology, Istanbul University-Cerrahpasa, Istanbul, TurkeyObjectives Superb microvascular imaging (SMI) provides a more sensitive assessment of small vessels compared with power and colour Doppler ultrasonography (PDUS and CDUS). We aimed to investigate the potential of SMI for use in research and clinical practice in Behçet syndrome (BS) and to gain a better understanding of erythema nodosum (EN) like and superficial thrombophlebitis (STM) lesions using SMI.Methods We studied 51 patients with BS and 31 patients with non-BS with red palpable lesions on physical examination. B-mode US, CDUS, PDUS and SMI were performed and recorded by the same radiologist and recorded images were additionally evaluated independently by another radiologist. Vessel-wall signal intensity of STM lesions by SMI was graded in four groups according to the percentages of the affected vessel-wall area (Grade 0: no signal, Grade 1: < 25%, Grade 2: 25%–50%, Grade 3: 50%–75% and Grade 4: >75%).Results The lesions of 26 patients with BS and 17 patients with non-BS were diagnosed as STM with CDUS. SMI of STM lesions revealed vessel-wall signals in 21/26 patients with BS (81%), in contrast to only 3/17 (18%) patients with non-BS. While 16 of 21 patients with BS (76%) had at least grade 2 signal, only 1 of 3 non-BS had it. Lesions of 25 BS and 11 non-BS were diagnosed as EN by CDUS and SMI showed no vessel-wall signal in these patients.Conclusions Evaluation of the vessel wall with SMI in BS may be a promising approach for showing inflammation as an inexpensive, non-invasive and reliable imaging method that does not require a contrast agent.https://rmdopen.bmj.com/content/11/2/e005382.full |
| spellingShingle | Gulen Hatemi Yesim Ozguler Melike Melikoğlu Sinem Nihal Esatoglu İbrahim Adaletli Yasemin Kayadibi Ugur Kimyon Ayse Kalyoncu Ucar Venous vessel-wall assessment with superb microvascular imaging in Behçet syndrome RMD Open |
| title | Venous vessel-wall assessment with superb microvascular imaging in Behçet syndrome |
| title_full | Venous vessel-wall assessment with superb microvascular imaging in Behçet syndrome |
| title_fullStr | Venous vessel-wall assessment with superb microvascular imaging in Behçet syndrome |
| title_full_unstemmed | Venous vessel-wall assessment with superb microvascular imaging in Behçet syndrome |
| title_short | Venous vessel-wall assessment with superb microvascular imaging in Behçet syndrome |
| title_sort | venous vessel wall assessment with superb microvascular imaging in behcet syndrome |
| url | https://rmdopen.bmj.com/content/11/2/e005382.full |
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