Prognostic factors in mesial temporal lobe epilepsy surgery

Eighty-four patients submitted to anterior temporal lobectomy were evaluated retrospectively in order to correlate the different type of simple partial seizure (SPS) and their prognostic implications in patients with mesial temporal sclerosis. The patients were divided in two groups following the cl...

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Main Authors: DANIEL M. S. PREVEDELLO, MARCOS C. SANDMANN, ALOIS EBNER
Format: Article
Language:English
Published: Thieme Revinter Publicações 2000-06-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000200001&tlng=en
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author DANIEL M. S. PREVEDELLO
MARCOS C. SANDMANN
ALOIS EBNER
author_facet DANIEL M. S. PREVEDELLO
MARCOS C. SANDMANN
ALOIS EBNER
author_sort DANIEL M. S. PREVEDELLO
collection DOAJ
description Eighty-four patients submitted to anterior temporal lobectomy were evaluated retrospectively in order to correlate the different type of simple partial seizure (SPS) and their prognostic implications in patients with mesial temporal sclerosis. The patients were divided in two groups following the classification of Engel; Group 1 (53 patients) included patients Class I (without seizures or of good outcome) and Group 2 (31 patients) included Classes II, III and IV (with seizures or of bad outcome). The two groups were compared and results showed no statistical difference in relation to the demographic aspects as sex, side of surgery, age at onset of seizures and time of the patients' postoperative follow-up. Statistical analysis revealed no relationship between type of SPS and outcome. SPS did not show a statistical value in localizing the side of pathology. However, when the two groups were compared statistically in terms of patients' ages at the time of surgery, and the time elapsed from the onset of the seizures to the surgical intervention, it was observed that Group 1 (of good outcome) had seizures for smaller interval (p <0.05) and was operated at an earlier age (p<0.02) than Group 2 (of bad outcome). The presence or the type of SPS can not be used as a prognostic measure; surgical therapy must be considered as soon as clinical resistance is demonstrated.
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spelling doaj-art-8a3d7e3d5378492f9b56716696822aa42025-08-20T03:37:50ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272000-06-01582A207213Prognostic factors in mesial temporal lobe epilepsy surgeryDANIEL M. S. PREVEDELLOMARCOS C. SANDMANN0ALOIS EBNER1Hospital Nossa Senhora das GraçasHospital Nossa Senhora das GraçasEighty-four patients submitted to anterior temporal lobectomy were evaluated retrospectively in order to correlate the different type of simple partial seizure (SPS) and their prognostic implications in patients with mesial temporal sclerosis. The patients were divided in two groups following the classification of Engel; Group 1 (53 patients) included patients Class I (without seizures or of good outcome) and Group 2 (31 patients) included Classes II, III and IV (with seizures or of bad outcome). The two groups were compared and results showed no statistical difference in relation to the demographic aspects as sex, side of surgery, age at onset of seizures and time of the patients' postoperative follow-up. Statistical analysis revealed no relationship between type of SPS and outcome. SPS did not show a statistical value in localizing the side of pathology. However, when the two groups were compared statistically in terms of patients' ages at the time of surgery, and the time elapsed from the onset of the seizures to the surgical intervention, it was observed that Group 1 (of good outcome) had seizures for smaller interval (p <0.05) and was operated at an earlier age (p<0.02) than Group 2 (of bad outcome). The presence or the type of SPS can not be used as a prognostic measure; surgical therapy must be considered as soon as clinical resistance is demonstrated.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000200001&tlng=ensimple partial seizurehippocampal sclerosismesial temporal sclerosistemporal epilepsyepilepsy surgery
spellingShingle DANIEL M. S. PREVEDELLO
MARCOS C. SANDMANN
ALOIS EBNER
Prognostic factors in mesial temporal lobe epilepsy surgery
Arquivos de Neuro-Psiquiatria
simple partial seizure
hippocampal sclerosis
mesial temporal sclerosis
temporal epilepsy
epilepsy surgery
title Prognostic factors in mesial temporal lobe epilepsy surgery
title_full Prognostic factors in mesial temporal lobe epilepsy surgery
title_fullStr Prognostic factors in mesial temporal lobe epilepsy surgery
title_full_unstemmed Prognostic factors in mesial temporal lobe epilepsy surgery
title_short Prognostic factors in mesial temporal lobe epilepsy surgery
title_sort prognostic factors in mesial temporal lobe epilepsy surgery
topic simple partial seizure
hippocampal sclerosis
mesial temporal sclerosis
temporal epilepsy
epilepsy surgery
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000200001&tlng=en
work_keys_str_mv AT danielmsprevedello prognosticfactorsinmesialtemporallobeepilepsysurgery
AT marcoscsandmann prognosticfactorsinmesialtemporallobeepilepsysurgery
AT aloisebner prognosticfactorsinmesialtemporallobeepilepsysurgery