Successful Primary Treatment of a Hydatidiform Mole with Methotrexate and EMA/CO
Background. The preferred treatment method of most hydatidiform moles is suction aspiration. In rare circumstances uterine abnormalities may preclude surgical treatment. Case. We report a case of complete molar pregnancy successfully treated with methotrexate followed by EMA/CO. A 38-year-old woman...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
|
| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2009/454161 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832545654674554880 |
|---|---|
| author | M. De Vos M. Leunen C. Fontaine Ph. De Sutter |
| author_facet | M. De Vos M. Leunen C. Fontaine Ph. De Sutter |
| author_sort | M. De Vos |
| collection | DOAJ |
| description | Background. The preferred treatment method of most hydatidiform moles is suction aspiration. In rare circumstances uterine abnormalities may preclude surgical treatment. Case. We report a case of complete molar pregnancy successfully treated with methotrexate followed by EMA/CO. A 38-year-old woman with a complete hydatidiform mole and multiple uterine fibroids underwent a failed attempt at suction aspiration. Following treatment with methotrexate, a nonmetastatic persistent trophoblastic tumour developed. Six cycles of EMA/CO led to complete remission. Conclusion. We propose that primary treatment of molar pregnancies with chemotherapy is a useful treatment option in cases where uterine abnormalities interfere with suction aspiration. |
| format | Article |
| id | doaj-art-8a326cf233884704bc5364da5cd2deee |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-8a326cf233884704bc5364da5cd2deee2025-02-03T07:25:10ZengWileyCase Reports in Medicine1687-96271687-96352009-01-01200910.1155/2009/454161454161Successful Primary Treatment of a Hydatidiform Mole with Methotrexate and EMA/COM. De Vos0M. Leunen1C. Fontaine2Ph. De Sutter3Department of Gynaecology, Academic Hospital, Brussels Free University - (VUB), UZ Brussel, 1090 Brussels, BelgiumDepartment of Gynaecology, Academic Hospital, Brussels Free University - (VUB), UZ Brussel, 1090 Brussels, BelgiumDepartment of Oncology, Academic Hospital, Brussels Free University - (VUB), UZ Brussel, 1090 Brussels, BelgiumDepartment of Gynaecology, Academic Hospital, Brussels Free University - (VUB), UZ Brussel, 1090 Brussels, BelgiumBackground. The preferred treatment method of most hydatidiform moles is suction aspiration. In rare circumstances uterine abnormalities may preclude surgical treatment. Case. We report a case of complete molar pregnancy successfully treated with methotrexate followed by EMA/CO. A 38-year-old woman with a complete hydatidiform mole and multiple uterine fibroids underwent a failed attempt at suction aspiration. Following treatment with methotrexate, a nonmetastatic persistent trophoblastic tumour developed. Six cycles of EMA/CO led to complete remission. Conclusion. We propose that primary treatment of molar pregnancies with chemotherapy is a useful treatment option in cases where uterine abnormalities interfere with suction aspiration.http://dx.doi.org/10.1155/2009/454161 |
| spellingShingle | M. De Vos M. Leunen C. Fontaine Ph. De Sutter Successful Primary Treatment of a Hydatidiform Mole with Methotrexate and EMA/CO Case Reports in Medicine |
| title | Successful Primary Treatment of a Hydatidiform Mole with Methotrexate and EMA/CO |
| title_full | Successful Primary Treatment of a Hydatidiform Mole with Methotrexate and EMA/CO |
| title_fullStr | Successful Primary Treatment of a Hydatidiform Mole with Methotrexate and EMA/CO |
| title_full_unstemmed | Successful Primary Treatment of a Hydatidiform Mole with Methotrexate and EMA/CO |
| title_short | Successful Primary Treatment of a Hydatidiform Mole with Methotrexate and EMA/CO |
| title_sort | successful primary treatment of a hydatidiform mole with methotrexate and ema co |
| url | http://dx.doi.org/10.1155/2009/454161 |
| work_keys_str_mv | AT mdevos successfulprimarytreatmentofahydatidiformmolewithmethotrexateandemaco AT mleunen successfulprimarytreatmentofahydatidiformmolewithmethotrexateandemaco AT cfontaine successfulprimarytreatmentofahydatidiformmolewithmethotrexateandemaco AT phdesutter successfulprimarytreatmentofahydatidiformmolewithmethotrexateandemaco |