Emerging Perspectives in Scaffold for Tissue Engineering in Oral Surgery
Bone regeneration is currently one of the most important and challenging tissue engineering approaches in regenerative medicine. Bone regeneration is a promising approach in dentistry and is considered an ideal clinical strategy in treating diseases, injuries, and defects of the maxillofacial region...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2017/4585401 |
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| author | Gabriele Ceccarelli Rossella Presta Laura Benedetti Maria Gabriella Cusella De Angelis Saturnino Marco Lupi Ruggero Rodriguez y Baena |
| author_facet | Gabriele Ceccarelli Rossella Presta Laura Benedetti Maria Gabriella Cusella De Angelis Saturnino Marco Lupi Ruggero Rodriguez y Baena |
| author_sort | Gabriele Ceccarelli |
| collection | DOAJ |
| description | Bone regeneration is currently one of the most important and challenging tissue engineering approaches in regenerative medicine. Bone regeneration is a promising approach in dentistry and is considered an ideal clinical strategy in treating diseases, injuries, and defects of the maxillofacial region. Advances in tissue engineering have resulted in the development of innovative scaffold designs, complemented by the progress made in cell-based therapies. In vitro bone regeneration can be achieved by the combination of stem cells, scaffolds, and bioactive factors. The biomimetic approach to create an ideal bone substitute provides strategies for developing combined scaffolds composed of adult stem cells with mesenchymal phenotype and different organic biomaterials (such as collagen and hyaluronic acid derivatives) or inorganic biomaterials such as manufactured polymers (polyglycolic acid (PGA), polylactic acid (PLA), and polycaprolactone). This review focuses on different biomaterials currently used in dentistry as scaffolds for bone regeneration in treating bone defects or in surgical techniques, such as sinus lift, horizontal and vertical bone grafts, or socket preservation. Our review would be of particular interest to medical and surgical researchers at the interface of cell biology, materials science, and tissue engineering, as well as industry-related manufacturers and researchers in healthcare, prosthetics, and 3D printing, too. |
| format | Article |
| id | doaj-art-8a30346a4aca4bd6aac5c4702ae8e94f |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-8a30346a4aca4bd6aac5c4702ae8e94f2025-02-03T01:02:45ZengWileyStem Cells International1687-966X1687-96782017-01-01201710.1155/2017/45854014585401Emerging Perspectives in Scaffold for Tissue Engineering in Oral SurgeryGabriele Ceccarelli0Rossella Presta1Laura Benedetti2Maria Gabriella Cusella De Angelis3Saturnino Marco Lupi4Ruggero Rodriguez y Baena5Department of Public Health, Experimental Medicine and Forensic, Human Anatomy Unit, University of Pavia, Via Forlanini 8, 27100 Pavia, ItalyDepartment of Clinico-Surgical, Diagnostic and Pediatric Sciences, School of Dentistry, University of Pavia, P.le Golgi 2, 27100 Pavia, ItalyDepartment of Public Health, Experimental Medicine and Forensic, Human Anatomy Unit, University of Pavia, Via Forlanini 8, 27100 Pavia, ItalyDepartment of Public Health, Experimental Medicine and Forensic, Human Anatomy Unit, University of Pavia, Via Forlanini 8, 27100 Pavia, ItalyDepartment of Clinico-Surgical, Diagnostic and Pediatric Sciences, School of Dentistry, University of Pavia, P.le Golgi 2, 27100 Pavia, ItalyDepartment of Clinico-Surgical, Diagnostic and Pediatric Sciences, School of Dentistry, University of Pavia, P.le Golgi 2, 27100 Pavia, ItalyBone regeneration is currently one of the most important and challenging tissue engineering approaches in regenerative medicine. Bone regeneration is a promising approach in dentistry and is considered an ideal clinical strategy in treating diseases, injuries, and defects of the maxillofacial region. Advances in tissue engineering have resulted in the development of innovative scaffold designs, complemented by the progress made in cell-based therapies. In vitro bone regeneration can be achieved by the combination of stem cells, scaffolds, and bioactive factors. The biomimetic approach to create an ideal bone substitute provides strategies for developing combined scaffolds composed of adult stem cells with mesenchymal phenotype and different organic biomaterials (such as collagen and hyaluronic acid derivatives) or inorganic biomaterials such as manufactured polymers (polyglycolic acid (PGA), polylactic acid (PLA), and polycaprolactone). This review focuses on different biomaterials currently used in dentistry as scaffolds for bone regeneration in treating bone defects or in surgical techniques, such as sinus lift, horizontal and vertical bone grafts, or socket preservation. Our review would be of particular interest to medical and surgical researchers at the interface of cell biology, materials science, and tissue engineering, as well as industry-related manufacturers and researchers in healthcare, prosthetics, and 3D printing, too.http://dx.doi.org/10.1155/2017/4585401 |
| spellingShingle | Gabriele Ceccarelli Rossella Presta Laura Benedetti Maria Gabriella Cusella De Angelis Saturnino Marco Lupi Ruggero Rodriguez y Baena Emerging Perspectives in Scaffold for Tissue Engineering in Oral Surgery Stem Cells International |
| title | Emerging Perspectives in Scaffold for Tissue Engineering in Oral Surgery |
| title_full | Emerging Perspectives in Scaffold for Tissue Engineering in Oral Surgery |
| title_fullStr | Emerging Perspectives in Scaffold for Tissue Engineering in Oral Surgery |
| title_full_unstemmed | Emerging Perspectives in Scaffold for Tissue Engineering in Oral Surgery |
| title_short | Emerging Perspectives in Scaffold for Tissue Engineering in Oral Surgery |
| title_sort | emerging perspectives in scaffold for tissue engineering in oral surgery |
| url | http://dx.doi.org/10.1155/2017/4585401 |
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