Uncovering the mechanistic basis of Rheum palmatum L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular docking, and experimental validation

Context Rheum palmatum L. (Rhubarb) has shown potential in managing Chronic Kidney Disease (CKD) but its protective mechanisms remain unclear.Objective This study investigates rhubarb’s therapeutic effects and underlying mechanisms in CKD.Materials and methods High-performance liquid chromatography...

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Bibliographic Details
Main Authors: Wenjing He, Zhen Wei, Siwei Li, Songji Han, Jing Ma, Lei Wu, Dan Lu, Guang Ta
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Pharmaceutical Biology
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Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2025.2543829
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