Ultrastructural Changes of the Peri-Tumoral Collagen Fibers and Fibrils Array in Different Stages of Mammary Cancer Progression

Ultrastructural Changes of the Peri-Tumoral Collagen Fibers and Fibrils Array in Different Stages of Mammary Cancer Progression

Breast cancer invasion and subsequent metastasis to distant tissues occur when cancer cells lose cell–cell contact, develop a migrating phenotype, and invade the basement membrane (BM) and the extracellular matrix (ECM) to penetrate blood and lymphatic vessels. The identification of the mechanisms w...

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Bibliographic Details
Main Authors: Marco Franchi, Valentina Masola, Maurizio Onisto, Leonardo Franchi, Sylvia Mangani, Vasiliki Zolota, Zoi Piperigkou, Nikos K. Karamanos
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
breast cancer
collagen fibers
collagen fibrils
extracellular matrix
Online Access:https://www.mdpi.com/2073-4409/14/13/1037
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