Gray-Level Co-Occurrence Matrix Uniformity Correction Algorithm in Positron Emission Tomographic Image: A Phantom Study

High uniformity of positron emission tomography (PET) images in the field of nuclear medicine is necessary to obtain excellent and stable data from the system. In this study, we aimed to apply and optimize a PET/magnetic resonance (MR) imaging system by approaching the gray-level co-occurrence matri...

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Main Authors: Kyuseok Kim, Youngjin Lee
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Photonics
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Online Access:https://www.mdpi.com/2304-6732/12/1/33
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author Kyuseok Kim
Youngjin Lee
author_facet Kyuseok Kim
Youngjin Lee
author_sort Kyuseok Kim
collection DOAJ
description High uniformity of positron emission tomography (PET) images in the field of nuclear medicine is necessary to obtain excellent and stable data from the system. In this study, we aimed to apply and optimize a PET/magnetic resonance (MR) imaging system by approaching the gray-level co-occurrence matrix (GLCM), which is known to be efficient in the uniformity correction of images. CAIPIRINHA Dixon-VIBE was used as an MR image acquisition pulse sequence for the fast and accurate attenuation correction of PET images, and the phantom was constructed by injecting NaCl and NaCl + NiSO<sub>4</sub> solutions. The lambda value of the GLCM algorithm for uniformity correction of the acquired PET images was optimized in terms of energy and contrast. By applying the GLCM algorithm optimized in terms of energy and contrast to the PET images of phantoms using NaCl and NaCl + NiSO<sub>4</sub> solutions, average percent image uniformity (PIU) values of 26.01 and 83.76 were derived, respectively. Compared to the original PET image, an improved PIU value of more than 30% was derived from the PET image to which the proposed optimized GLCM algorithm was applied. In conclusion, we demonstrated that an algorithm optimized in terms of the GLCM energy and contrast can improve the uniformity of PET images.
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spelling doaj-art-89df35d9d3f44865b19700e15dab8dc22025-01-24T13:46:16ZengMDPI AGPhotonics2304-67322025-01-011213310.3390/photonics12010033Gray-Level Co-Occurrence Matrix Uniformity Correction Algorithm in Positron Emission Tomographic Image: A Phantom StudyKyuseok Kim0Youngjin Lee1Department of Biomedical Engineering, Eulji University, 553, Sanseong-daero, Sujeong-gu, Seongnam-si 13135, Republic of KoreaDepartment of Radiological Science, Gachon University, 191, Hambakmoe-ro, Yeonsu-gu, Incheon 21936, Republic of KoreaHigh uniformity of positron emission tomography (PET) images in the field of nuclear medicine is necessary to obtain excellent and stable data from the system. In this study, we aimed to apply and optimize a PET/magnetic resonance (MR) imaging system by approaching the gray-level co-occurrence matrix (GLCM), which is known to be efficient in the uniformity correction of images. CAIPIRINHA Dixon-VIBE was used as an MR image acquisition pulse sequence for the fast and accurate attenuation correction of PET images, and the phantom was constructed by injecting NaCl and NaCl + NiSO<sub>4</sub> solutions. The lambda value of the GLCM algorithm for uniformity correction of the acquired PET images was optimized in terms of energy and contrast. By applying the GLCM algorithm optimized in terms of energy and contrast to the PET images of phantoms using NaCl and NaCl + NiSO<sub>4</sub> solutions, average percent image uniformity (PIU) values of 26.01 and 83.76 were derived, respectively. Compared to the original PET image, an improved PIU value of more than 30% was derived from the PET image to which the proposed optimized GLCM algorithm was applied. In conclusion, we demonstrated that an algorithm optimized in terms of the GLCM energy and contrast can improve the uniformity of PET images.https://www.mdpi.com/2304-6732/12/1/33positron emission tomography (PET)attenuation correctiongray-level co-occurrence matrix (GLCM)parameter optimizationuniformity correctionquantitative evaluation of image
spellingShingle Kyuseok Kim
Youngjin Lee
Gray-Level Co-Occurrence Matrix Uniformity Correction Algorithm in Positron Emission Tomographic Image: A Phantom Study
Photonics
positron emission tomography (PET)
attenuation correction
gray-level co-occurrence matrix (GLCM)
parameter optimization
uniformity correction
quantitative evaluation of image
title Gray-Level Co-Occurrence Matrix Uniformity Correction Algorithm in Positron Emission Tomographic Image: A Phantom Study
title_full Gray-Level Co-Occurrence Matrix Uniformity Correction Algorithm in Positron Emission Tomographic Image: A Phantom Study
title_fullStr Gray-Level Co-Occurrence Matrix Uniformity Correction Algorithm in Positron Emission Tomographic Image: A Phantom Study
title_full_unstemmed Gray-Level Co-Occurrence Matrix Uniformity Correction Algorithm in Positron Emission Tomographic Image: A Phantom Study
title_short Gray-Level Co-Occurrence Matrix Uniformity Correction Algorithm in Positron Emission Tomographic Image: A Phantom Study
title_sort gray level co occurrence matrix uniformity correction algorithm in positron emission tomographic image a phantom study
topic positron emission tomography (PET)
attenuation correction
gray-level co-occurrence matrix (GLCM)
parameter optimization
uniformity correction
quantitative evaluation of image
url https://www.mdpi.com/2304-6732/12/1/33
work_keys_str_mv AT kyuseokkim graylevelcooccurrencematrixuniformitycorrectionalgorithminpositronemissiontomographicimageaphantomstudy
AT youngjinlee graylevelcooccurrencematrixuniformitycorrectionalgorithminpositronemissiontomographicimageaphantomstudy