Development of a novel Ga-containing hydroxyapatite/chlorhexidine biomaterial with antibacterial properties for future application in bone tissue engineering: an experimental and theoretical study

Development of a novel Ga-containing hydroxyapatite/chlorhexidine biomaterial with antibacterial properties for future application in bone tissue engineering: an experimental and theoretical study

Abstract This study focuses on synthesizing gallium-containing hydroxyapatite (Ga-HA) with chlorhexidine (CLX) for potential use in bone and dental tissue restoration. The Ga-HA/CLX materials were prepared using a suspension-precipitation method and were surface-functionalized with varying CLX conce...

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Main Authors: Ewerton Gomes Vieira, Ricardo Barbosa Sousa, Marcos Pereira da Silva, Régis Casimiro Leal, Anderson Gomes Vieira, Wiury Chaves de Abreu, André L. Menezes de Oliveira, Maria Gardênnia da Fonseca, Santiago Medina Carrasco, Josy Anteveli Osajima, Edson C. Silva-Filho
Format: Article
Language:English
Published: Associação Brasileira de Cerâmica 2025-04-01
Series:Cerâmica
Subjects:
Antibacterial properties
Bone repair
Chlorhexidine-functionalized biomaterials
Density Functional Theory (DFT)
Surface functionalization
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132025000100309&lng=en&tlng=en
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