The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project
Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson’s disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a...
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Language: | English |
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Wiley
2011-01-01
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Series: | Parkinson's Disease |
Online Access: | http://dx.doi.org/10.4061/2011/125271 |
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author | Vinod Metta Kartik Logishetty P. Martinez-Martin Heather M. Gage P. E. S. Schartau T. K. Kaluarachchi Anne Martin Per Odin P. Barone Fabrizio Stocchi A. Antonini K. Ray Chaudhuri |
author_facet | Vinod Metta Kartik Logishetty P. Martinez-Martin Heather M. Gage P. E. S. Schartau T. K. Kaluarachchi Anne Martin Per Odin P. Barone Fabrizio Stocchi A. Antonini K. Ray Chaudhuri |
author_sort | Vinod Metta |
collection | DOAJ |
description | Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson’s disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a validated visual analogue scale and the Parkinson’s disease nonmotor symptoms scale (PDNMSS) was correlated with other motor and nonmotor comorbidities. In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson’s disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis. |
format | Article |
id | doaj-art-8993ef34da5544a8b0bf2b6d08b8a80d |
institution | Kabale University |
issn | 2042-0080 |
language | English |
publishDate | 2011-01-01 |
publisher | Wiley |
record_format | Article |
series | Parkinson's Disease |
spelling | doaj-art-8993ef34da5544a8b0bf2b6d08b8a80d2025-02-03T01:02:00ZengWileyParkinson's Disease2042-00802011-01-01201110.4061/2011/125271125271The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation ProjectVinod Metta0Kartik Logishetty1P. Martinez-Martin2Heather M. Gage3P. E. S. Schartau4T. K. Kaluarachchi5Anne Martin6Per Odin7P. Barone8Fabrizio Stocchi9A. Antonini10K. Ray Chaudhuri11National Parkinson Foundation Centre of Excellence, King’s College Hospital, King’s College London, Denmark Hill Campus, 9th Floor, Ruskin Wing, London SE5 9RS, UKNational Parkinson Foundation Centre of Excellence, King’s College Hospital, King’s College London, Denmark Hill Campus, 9th Floor, Ruskin Wing, London SE5 9RS, UKAlzheimer Disease Research Unit, CIEN Foundation, Carlos III Institute of Health, Alzheimer Center Reina Sofia Foundation, Madrid, SpainUniversity of Surrey, Surrey GU2 7XH, UKUniversity Hospital Lewisham, London SE13 6LH, UKUniversity Hospital Lewisham, London SE13 6LH, UKNational Parkinson Foundation Centre of Excellence, King’s College Hospital, King’s College London, Denmark Hill Campus, 9th Floor, Ruskin Wing, London SE5 9RS, UKDepartment of Neurology, University Hospital, Lund University, Lund, SwedenDepartment of Neurological Sciences, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyDepartment of Neurology, IRCCS San Raffaele, 00163 Rome, ItalyDepartment of Neurology, IRCCS San Camillo Venice and University of Padua, 35122 Padua, ItalyNational Parkinson Foundation Centre of Excellence, King’s College Hospital, King’s College London, Denmark Hill Campus, 9th Floor, Ruskin Wing, London SE5 9RS, UKFatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson’s disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a validated visual analogue scale and the Parkinson’s disease nonmotor symptoms scale (PDNMSS) was correlated with other motor and nonmotor comorbidities. In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson’s disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis.http://dx.doi.org/10.4061/2011/125271 |
spellingShingle | Vinod Metta Kartik Logishetty P. Martinez-Martin Heather M. Gage P. E. S. Schartau T. K. Kaluarachchi Anne Martin Per Odin P. Barone Fabrizio Stocchi A. Antonini K. Ray Chaudhuri The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project Parkinson's Disease |
title | The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project |
title_full | The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project |
title_fullStr | The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project |
title_full_unstemmed | The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project |
title_short | The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project |
title_sort | possible clinical predictors of fatigue in parkinson s disease a study of 135 patients as part of international nonmotor scale validation project |
url | http://dx.doi.org/10.4061/2011/125271 |
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