The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project

Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson’s disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a...

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Main Authors: Vinod Metta, Kartik Logishetty, P. Martinez-Martin, Heather M. Gage, P. E. S. Schartau, T. K. Kaluarachchi, Anne Martin, Per Odin, P. Barone, Fabrizio Stocchi, A. Antonini, K. Ray Chaudhuri
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.4061/2011/125271
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author Vinod Metta
Kartik Logishetty
P. Martinez-Martin
Heather M. Gage
P. E. S. Schartau
T. K. Kaluarachchi
Anne Martin
Per Odin
P. Barone
Fabrizio Stocchi
A. Antonini
K. Ray Chaudhuri
author_facet Vinod Metta
Kartik Logishetty
P. Martinez-Martin
Heather M. Gage
P. E. S. Schartau
T. K. Kaluarachchi
Anne Martin
Per Odin
P. Barone
Fabrizio Stocchi
A. Antonini
K. Ray Chaudhuri
author_sort Vinod Metta
collection DOAJ
description Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson’s disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a validated visual analogue scale and the Parkinson’s disease nonmotor symptoms scale (PDNMSS) was correlated with other motor and nonmotor comorbidities. In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson’s disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis.
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institution Kabale University
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publishDate 2011-01-01
publisher Wiley
record_format Article
series Parkinson's Disease
spelling doaj-art-8993ef34da5544a8b0bf2b6d08b8a80d2025-02-03T01:02:00ZengWileyParkinson's Disease2042-00802011-01-01201110.4061/2011/125271125271The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation ProjectVinod Metta0Kartik Logishetty1P. Martinez-Martin2Heather M. Gage3P. E. S. Schartau4T. K. Kaluarachchi5Anne Martin6Per Odin7P. Barone8Fabrizio Stocchi9A. Antonini10K. Ray Chaudhuri11National Parkinson Foundation Centre of Excellence, King’s College Hospital, King’s College London, Denmark Hill Campus, 9th Floor, Ruskin Wing, London SE5 9RS, UKNational Parkinson Foundation Centre of Excellence, King’s College Hospital, King’s College London, Denmark Hill Campus, 9th Floor, Ruskin Wing, London SE5 9RS, UKAlzheimer Disease Research Unit, CIEN Foundation, Carlos III Institute of Health, Alzheimer Center Reina Sofia Foundation, Madrid, SpainUniversity of Surrey, Surrey GU2 7XH, UKUniversity Hospital Lewisham, London SE13 6LH, UKUniversity Hospital Lewisham, London SE13 6LH, UKNational Parkinson Foundation Centre of Excellence, King’s College Hospital, King’s College London, Denmark Hill Campus, 9th Floor, Ruskin Wing, London SE5 9RS, UKDepartment of Neurology, University Hospital, Lund University, Lund, SwedenDepartment of Neurological Sciences, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyDepartment of Neurology, IRCCS San Raffaele, 00163 Rome, ItalyDepartment of Neurology, IRCCS San Camillo Venice and University of Padua, 35122 Padua, ItalyNational Parkinson Foundation Centre of Excellence, King’s College Hospital, King’s College London, Denmark Hill Campus, 9th Floor, Ruskin Wing, London SE5 9RS, UKFatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson’s disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a validated visual analogue scale and the Parkinson’s disease nonmotor symptoms scale (PDNMSS) was correlated with other motor and nonmotor comorbidities. In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson’s disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis.http://dx.doi.org/10.4061/2011/125271
spellingShingle Vinod Metta
Kartik Logishetty
P. Martinez-Martin
Heather M. Gage
P. E. S. Schartau
T. K. Kaluarachchi
Anne Martin
Per Odin
P. Barone
Fabrizio Stocchi
A. Antonini
K. Ray Chaudhuri
The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project
Parkinson's Disease
title The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project
title_full The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project
title_fullStr The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project
title_full_unstemmed The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project
title_short The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project
title_sort possible clinical predictors of fatigue in parkinson s disease a study of 135 patients as part of international nonmotor scale validation project
url http://dx.doi.org/10.4061/2011/125271
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