Dedifferentiated Liposarcoma Arising in an Esophageal Polyp: A Case Report

Liposarcoma is one of the most common sarcomas in adults, but only rarely presents as an esophageal primary. There have been several reports of well-differentiated liposarcoma (WDL) arising in the esophagus, but we present a case of dedifferentiated liposarcoma (DL) presenting as a large esophageal...

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Main Authors: Jorge Torres-Mora, Ann Moyer, Mark Topazian, Jeffrey Alexander, Tsung-Teh Wu, Amber Seys, Karen Fritchie
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2012/141693
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author Jorge Torres-Mora
Ann Moyer
Mark Topazian
Jeffrey Alexander
Tsung-Teh Wu
Amber Seys
Karen Fritchie
author_facet Jorge Torres-Mora
Ann Moyer
Mark Topazian
Jeffrey Alexander
Tsung-Teh Wu
Amber Seys
Karen Fritchie
author_sort Jorge Torres-Mora
collection DOAJ
description Liposarcoma is one of the most common sarcomas in adults, but only rarely presents as an esophageal primary. There have been several reports of well-differentiated liposarcoma (WDL) arising in the esophagus, but we present a case of dedifferentiated liposarcoma (DL) presenting as a large esophageal polyp. We believe this is the first reported case of DL of the esophagus with morphologic evidence of both well-differentiated and dedifferentiated components. The diagnosis was confirmed by demonstration of CPM gene amplification by fluorescence in situ hybridization (FISH).
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institution Kabale University
issn 2090-6528
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language English
publishDate 2012-01-01
publisher Wiley
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-89874c42de464d1bbae35f43eb66516e2025-02-03T06:01:45ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362012-01-01201210.1155/2012/141693141693Dedifferentiated Liposarcoma Arising in an Esophageal Polyp: A Case ReportJorge Torres-Mora0Ann Moyer1Mark Topazian2Jeffrey Alexander3Tsung-Teh Wu4Amber Seys5Karen Fritchie6Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USADepartment of Gastroenterology, Mayo Clinic, Rochester, MN 55905, USADepartment of Gastroenterology, Mayo Clinic, Rochester, MN 55905, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USALiposarcoma is one of the most common sarcomas in adults, but only rarely presents as an esophageal primary. There have been several reports of well-differentiated liposarcoma (WDL) arising in the esophagus, but we present a case of dedifferentiated liposarcoma (DL) presenting as a large esophageal polyp. We believe this is the first reported case of DL of the esophagus with morphologic evidence of both well-differentiated and dedifferentiated components. The diagnosis was confirmed by demonstration of CPM gene amplification by fluorescence in situ hybridization (FISH).http://dx.doi.org/10.1155/2012/141693
spellingShingle Jorge Torres-Mora
Ann Moyer
Mark Topazian
Jeffrey Alexander
Tsung-Teh Wu
Amber Seys
Karen Fritchie
Dedifferentiated Liposarcoma Arising in an Esophageal Polyp: A Case Report
Case Reports in Gastrointestinal Medicine
title Dedifferentiated Liposarcoma Arising in an Esophageal Polyp: A Case Report
title_full Dedifferentiated Liposarcoma Arising in an Esophageal Polyp: A Case Report
title_fullStr Dedifferentiated Liposarcoma Arising in an Esophageal Polyp: A Case Report
title_full_unstemmed Dedifferentiated Liposarcoma Arising in an Esophageal Polyp: A Case Report
title_short Dedifferentiated Liposarcoma Arising in an Esophageal Polyp: A Case Report
title_sort dedifferentiated liposarcoma arising in an esophageal polyp a case report
url http://dx.doi.org/10.1155/2012/141693
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