Fructose regulates M1 macrophage polarisation by promoting glycolysis

Fructose regulates M1 macrophage polarisation by promoting glycolysis

Objective To investigate the regulatory effect of fructose (Fru) on the polarization of M1 macrophages induced by lipopolysaccharide (LPS) and interferon gamma (IFN-γ) and its possible mechanism. Methods The experiment was divided into M0 group (THP-1 cells were stimulated with 100 nmol/L phorbol es...

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Bibliographic Details
Main Authors: WANG Minghong, LIU Yubing, WANG Xinhang, LI Han, CHEN Sihong, ZHANG Minhua, PENG Yang, LU Cailing, TANG Shen, LI Xiyi
Format: Article
Language:zho
Published: Editorial Office of Journal of Guangxi Medical University 2025-04-01
Series:Guangxi Yike Daxue xuebao
Subjects:
fructose
m1 macrophages
glycolysis
polarisation
phagocytic ability
Online Access:https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2025.02.002
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