Chemical Immobilization of Sloth Bears (Melursus ursinus) with Ketamine Hydrochloride and Xylazine Hydrochloride: Hematology and Serum Biochemical Values

The present study was conducted to define the physiological responses of captive sloth bears immobilized with ketamine hydrochloride and xylazine hydrochloride and to determine and compare the values of hematology and serum biochemical parameters between sexes. A total of 15 sloth bears were immobil...

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Main Authors: M. Veeraselvam, R. Sridhar, P. Perumal, M. G. Jayathangaraj
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Veterinary Medicine International
Online Access:http://dx.doi.org/10.1155/2014/341047
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author M. Veeraselvam
R. Sridhar
P. Perumal
M. G. Jayathangaraj
author_facet M. Veeraselvam
R. Sridhar
P. Perumal
M. G. Jayathangaraj
author_sort M. Veeraselvam
collection DOAJ
description The present study was conducted to define the physiological responses of captive sloth bears immobilized with ketamine hydrochloride and xylazine hydrochloride and to determine and compare the values of hematology and serum biochemical parameters between sexes. A total of 15 sloth bears were immobilized using combination of ketamine hydrochloride and xylazine hydrochloride drugs at the dose rate of 5.0 milligram (mg) per kg body weight and 2.0 mg per kg body weight, respectively. The use of combination of these drugs was found satisfactory for the chemical immobilization of captive sloth bears. There were no significant differences observed in induction time and recovery time and physiological parameters such as heart rate, respiratory rate, and rectal temperature between sexes. Health related parameters comprising hematological values like packed cell volume (PCV), hemoglobin (Hb), red blood cell count (RBC), erythrocyte indices, and so forth and biochemical values like total protein, blood urea nitrogen (BUN), creatinine, alkaline amino-transferase (ALT), aspartate amino-transferase (AST), and so forth were estimated in 11 (5 males and 6 females) apparently healthy bears. Comparison between sexes revealed significant difference in PCV (P<0.05) and mean corpuscular hemoglobin concentration (MCHC) (P<0.05). The study might help to evaluate health profiles of sloth bears for appropriate line treatment.
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institution Kabale University
issn 2090-8113
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publisher Wiley
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series Veterinary Medicine International
spelling doaj-art-896d3083707749b88366982b8b4547062025-02-03T01:02:28ZengWileyVeterinary Medicine International2090-81132042-00482014-01-01201410.1155/2014/341047341047Chemical Immobilization of Sloth Bears (Melursus ursinus) with Ketamine Hydrochloride and Xylazine Hydrochloride: Hematology and Serum Biochemical ValuesM. Veeraselvam0R. Sridhar1P. Perumal2M. G. Jayathangaraj3Department of Wild Life Science, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai 600 007, IndiaDepartment of Wild Life Science, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai 600 007, IndiaNational Research Centre on Mithun, ICAR, Jharnapani, Nagaland 797106, IndiaDepartment of Wild Life Science, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai 600 007, IndiaThe present study was conducted to define the physiological responses of captive sloth bears immobilized with ketamine hydrochloride and xylazine hydrochloride and to determine and compare the values of hematology and serum biochemical parameters between sexes. A total of 15 sloth bears were immobilized using combination of ketamine hydrochloride and xylazine hydrochloride drugs at the dose rate of 5.0 milligram (mg) per kg body weight and 2.0 mg per kg body weight, respectively. The use of combination of these drugs was found satisfactory for the chemical immobilization of captive sloth bears. There were no significant differences observed in induction time and recovery time and physiological parameters such as heart rate, respiratory rate, and rectal temperature between sexes. Health related parameters comprising hematological values like packed cell volume (PCV), hemoglobin (Hb), red blood cell count (RBC), erythrocyte indices, and so forth and biochemical values like total protein, blood urea nitrogen (BUN), creatinine, alkaline amino-transferase (ALT), aspartate amino-transferase (AST), and so forth were estimated in 11 (5 males and 6 females) apparently healthy bears. Comparison between sexes revealed significant difference in PCV (P<0.05) and mean corpuscular hemoglobin concentration (MCHC) (P<0.05). The study might help to evaluate health profiles of sloth bears for appropriate line treatment.http://dx.doi.org/10.1155/2014/341047
spellingShingle M. Veeraselvam
R. Sridhar
P. Perumal
M. G. Jayathangaraj
Chemical Immobilization of Sloth Bears (Melursus ursinus) with Ketamine Hydrochloride and Xylazine Hydrochloride: Hematology and Serum Biochemical Values
Veterinary Medicine International
title Chemical Immobilization of Sloth Bears (Melursus ursinus) with Ketamine Hydrochloride and Xylazine Hydrochloride: Hematology and Serum Biochemical Values
title_full Chemical Immobilization of Sloth Bears (Melursus ursinus) with Ketamine Hydrochloride and Xylazine Hydrochloride: Hematology and Serum Biochemical Values
title_fullStr Chemical Immobilization of Sloth Bears (Melursus ursinus) with Ketamine Hydrochloride and Xylazine Hydrochloride: Hematology and Serum Biochemical Values
title_full_unstemmed Chemical Immobilization of Sloth Bears (Melursus ursinus) with Ketamine Hydrochloride and Xylazine Hydrochloride: Hematology and Serum Biochemical Values
title_short Chemical Immobilization of Sloth Bears (Melursus ursinus) with Ketamine Hydrochloride and Xylazine Hydrochloride: Hematology and Serum Biochemical Values
title_sort chemical immobilization of sloth bears melursus ursinus with ketamine hydrochloride and xylazine hydrochloride hematology and serum biochemical values
url http://dx.doi.org/10.1155/2014/341047
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