Pembrolizumab Therapy Leading to Complete Remission for Recurrence of Pulmonary Metastases after their Resection and Radical Cystectomy following Gemcitabine and Cisplatin Therapy
A 64-year-old man was diagnosed with invasive bladder and right lower ureteral urothelial cancer with right pelvic lymph node and lung metastases. He received four courses of gemcitabine and cisplatin therapy. He underwent lung metastasectomy and radical cystoprostatectomy, with not only primary les...
Saved in:
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2024-01-01
|
Series: | Case Reports in Urology |
Online Access: | http://dx.doi.org/10.1155/2024/5586448 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832553070792278016 |
---|---|
author | Kyohei Ishida Go Hasegawa Takehisa Hashimoto Yohei Ikeda Noboru Hara Tsutomu Nishiyama |
author_facet | Kyohei Ishida Go Hasegawa Takehisa Hashimoto Yohei Ikeda Noboru Hara Tsutomu Nishiyama |
author_sort | Kyohei Ishida |
collection | DOAJ |
description | A 64-year-old man was diagnosed with invasive bladder and right lower ureteral urothelial cancer with right pelvic lymph node and lung metastases. He received four courses of gemcitabine and cisplatin therapy. He underwent lung metastasectomy and radical cystoprostatectomy, with not only primary lesions but also metastatic lesions showing a complete response. New multiple lung metastases were revealed five months after adjuvant chemotherapy. On starting pembrolizumab therapy, the metastatic lesions are notably reduced in size. He is currently receiving pembrolizumab therapy, and no recurrence has been observed for over one year. |
format | Article |
id | doaj-art-89518e93423642f799b969f2e31b4f07 |
institution | Kabale University |
issn | 2090-6978 |
language | English |
publishDate | 2024-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Urology |
spelling | doaj-art-89518e93423642f799b969f2e31b4f072025-02-03T05:57:04ZengWileyCase Reports in Urology2090-69782024-01-01202410.1155/2024/5586448Pembrolizumab Therapy Leading to Complete Remission for Recurrence of Pulmonary Metastases after their Resection and Radical Cystectomy following Gemcitabine and Cisplatin TherapyKyohei Ishida0Go Hasegawa1Takehisa Hashimoto2Yohei Ikeda3Noboru Hara4Tsutomu Nishiyama5Department of UrologyDepartment of PathologyDepartment of Respiratory SurgeryDepartment of Diagnostic RadiologyDepartment of UrologyDepartment of UrologyA 64-year-old man was diagnosed with invasive bladder and right lower ureteral urothelial cancer with right pelvic lymph node and lung metastases. He received four courses of gemcitabine and cisplatin therapy. He underwent lung metastasectomy and radical cystoprostatectomy, with not only primary lesions but also metastatic lesions showing a complete response. New multiple lung metastases were revealed five months after adjuvant chemotherapy. On starting pembrolizumab therapy, the metastatic lesions are notably reduced in size. He is currently receiving pembrolizumab therapy, and no recurrence has been observed for over one year.http://dx.doi.org/10.1155/2024/5586448 |
spellingShingle | Kyohei Ishida Go Hasegawa Takehisa Hashimoto Yohei Ikeda Noboru Hara Tsutomu Nishiyama Pembrolizumab Therapy Leading to Complete Remission for Recurrence of Pulmonary Metastases after their Resection and Radical Cystectomy following Gemcitabine and Cisplatin Therapy Case Reports in Urology |
title | Pembrolizumab Therapy Leading to Complete Remission for Recurrence of Pulmonary Metastases after their Resection and Radical Cystectomy following Gemcitabine and Cisplatin Therapy |
title_full | Pembrolizumab Therapy Leading to Complete Remission for Recurrence of Pulmonary Metastases after their Resection and Radical Cystectomy following Gemcitabine and Cisplatin Therapy |
title_fullStr | Pembrolizumab Therapy Leading to Complete Remission for Recurrence of Pulmonary Metastases after their Resection and Radical Cystectomy following Gemcitabine and Cisplatin Therapy |
title_full_unstemmed | Pembrolizumab Therapy Leading to Complete Remission for Recurrence of Pulmonary Metastases after their Resection and Radical Cystectomy following Gemcitabine and Cisplatin Therapy |
title_short | Pembrolizumab Therapy Leading to Complete Remission for Recurrence of Pulmonary Metastases after their Resection and Radical Cystectomy following Gemcitabine and Cisplatin Therapy |
title_sort | pembrolizumab therapy leading to complete remission for recurrence of pulmonary metastases after their resection and radical cystectomy following gemcitabine and cisplatin therapy |
url | http://dx.doi.org/10.1155/2024/5586448 |
work_keys_str_mv | AT kyoheiishida pembrolizumabtherapyleadingtocompleteremissionforrecurrenceofpulmonarymetastasesaftertheirresectionandradicalcystectomyfollowinggemcitabineandcisplatintherapy AT gohasegawa pembrolizumabtherapyleadingtocompleteremissionforrecurrenceofpulmonarymetastasesaftertheirresectionandradicalcystectomyfollowinggemcitabineandcisplatintherapy AT takehisahashimoto pembrolizumabtherapyleadingtocompleteremissionforrecurrenceofpulmonarymetastasesaftertheirresectionandradicalcystectomyfollowinggemcitabineandcisplatintherapy AT yoheiikeda pembrolizumabtherapyleadingtocompleteremissionforrecurrenceofpulmonarymetastasesaftertheirresectionandradicalcystectomyfollowinggemcitabineandcisplatintherapy AT noboruhara pembrolizumabtherapyleadingtocompleteremissionforrecurrenceofpulmonarymetastasesaftertheirresectionandradicalcystectomyfollowinggemcitabineandcisplatintherapy AT tsutomunishiyama pembrolizumabtherapyleadingtocompleteremissionforrecurrenceofpulmonarymetastasesaftertheirresectionandradicalcystectomyfollowinggemcitabineandcisplatintherapy |