The mechanisms and clinical significance of CD8+ T cell exhaustion in anti-tumor immunity
CD8+ T cell exhaustion, a critical challenge in the immune response to cancer, is characterized by a profound decline in the functionality of effector CD8+ T cells. This state of exhaustion is accompanied by the upregulation of various inhibitory receptors and significant shifts in both transcriptio...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
China Anti-Cancer Association
2025-05-01
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| Series: | Cancer Biology & Medicine |
| Subjects: | |
| Online Access: | https://www.cancerbiomed.org/content/22/5/460 |
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