The Pharmacology of Acute Lung Injury in Sepsis
Acute lung injury (ALI) secondary to sepsis is one of the leading causes of death in sepsis. As such, many pharmacologic and nonpharmacologic strategies have been employed to attenuate its course. Very few of these strategies have proven beneficial. In this paper, we discuss the epidemiology and pat...
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Main Author: | |
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Format: | Article |
Language: | English |
Published: |
Wiley
2011-01-01
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Series: | Advances in Pharmacological Sciences |
Online Access: | http://dx.doi.org/10.1155/2011/254619 |
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Summary: | Acute lung injury (ALI) secondary to sepsis is one of the leading causes of death in sepsis. As such, many pharmacologic and nonpharmacologic strategies have been employed to attenuate its course. Very few of these strategies have proven beneficial. In this paper, we discuss the epidemiology and pathophysiology of ALI, commonly employed pharmacologic and nonpharmacologic treatments, and innovative therapeutic modalities that will likely be the focus of future trials. |
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ISSN: | 1687-6334 1687-6342 |