Functional characterization of endocytic signals in the SynDIG/PRRT family members SynDIG1 and SynDIG4 in heterologous cells and neurons

Functional characterization of endocytic signals in the SynDIG/PRRT family members SynDIG1 and SynDIG4 in heterologous cells and neurons

The transmembrane protein Synapse Differentiation Induced Gene 4 (SynDIG4), also known as Proline-rich transmembrane protein 1 (PRRT1), is an AMPA-type glutamate receptor (AMPAR) auxiliary factor that is necessary for maintaining extra-synaptic pools of GluA1. Loss of SynDIG4, and the subsequent dec...

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Bibliographic Details
Main Authors:	David J. Speca, Chun-Wei He, Christina M. Meyer, Erin C. Scott, Elva Díaz
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Cellular Neuroscience
Subjects:	SynDIG1 Capucin SynDIG4 IFITM3 AP2 GluA1
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2024.1526034/full
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