A review of salivary composition changes induced by fasting and its impact on health
Human saliva is an indispensable fluid that maintains a healthy oral cavity which otherwise can lead to oral diseases (dental caries and periodontitis). In addition, salivary metabolites and microbiome profile provide early detection of systemic diseases such as cancer and obesity. Salivary diagnost...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2024-01-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453023001416 |
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| author | Nurul Fadhilah Kamalul Aripin N. Idayu Zahid Mohd Aizat Abdul Rahim Hashim Yaacob Parvez I. Haris Zubaidah Haji Abd. Rahim Rauzah Hashim |
| author_facet | Nurul Fadhilah Kamalul Aripin N. Idayu Zahid Mohd Aizat Abdul Rahim Hashim Yaacob Parvez I. Haris Zubaidah Haji Abd. Rahim Rauzah Hashim |
| author_sort | Nurul Fadhilah Kamalul Aripin |
| collection | DOAJ |
| description | Human saliva is an indispensable fluid that maintains a healthy oral cavity which otherwise can lead to oral diseases (dental caries and periodontitis). In addition, salivary metabolites and microbiome profile provide early detection of systemic diseases such as cancer and obesity. Salivary diagnostic has gained popularity due to its non-invasive sampling technique. Fasting (abstinence from food or drink or both) research for weight loss and improve health is common, but studies using fasting saliva are scarce. Some metabolites in fasting saliva have been reported with interesting results, which can be enhanced by considering different confounding factors. For example, fasting saliva contains higher salivary nitrite, which is related to nitric oxide (NO). NO is a vasodilator supporting the healthy function of endothelial cells and its deficiency is connected to many diseases. The timely supply of NO through exogenous and endogenous means is highlighted and the potential advantage of fasting salivary composition changes in relation to COVID-19 infection is speculated. This review aims to provide a general discussion on the salivary composition, properties, and functions of the whole saliva, including the health benefits of fasting. |
| format | Article |
| id | doaj-art-893b7eb896154175b5babf566d93125e |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-893b7eb896154175b5babf566d93125e2025-02-03T02:51:42ZengTsinghua University PressFood Science and Human Wellness2213-45302024-01-011315064A review of salivary composition changes induced by fasting and its impact on healthNurul Fadhilah Kamalul Aripin0N. Idayu Zahid1Mohd Aizat Abdul Rahim2Hashim Yaacob3Parvez I. Haris4Zubaidah Haji Abd. Rahim5Rauzah Hashim6School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, Shah Alam 40450, Malaysia; Centre for Fundamental and Frontier Sciences in Nanostructure Self-Assembly, Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, MalaysiaCentre for Fundamental and Frontier Sciences in Nanostructure Self-Assembly, Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, MalaysiaDepartment of Oral and Craniofacial Sciences, Faculty of Dentistry, Universiti Malaya, Kuala Lumpur 50603, MalaysiaUMSC Dental Specialist Clinic, UM Dentistry Tower, Universiti Malaya, Medical Centre, Kuala Lumpur 50603, MalaysiaLeicester School of Allied Health Sciences, De Montfort University, Leicester LE1 9BH, United KingdomChancellery (Research and Innovation), Universiti Malaya, Kuala Lumpur 50603, Malaysia; Corresponding authors.Centre for Fundamental and Frontier Sciences in Nanostructure Self-Assembly, Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia; Chancellery (Research and Innovation), Universiti Malaya, Kuala Lumpur 50603, Malaysia; Corresponding authors.Human saliva is an indispensable fluid that maintains a healthy oral cavity which otherwise can lead to oral diseases (dental caries and periodontitis). In addition, salivary metabolites and microbiome profile provide early detection of systemic diseases such as cancer and obesity. Salivary diagnostic has gained popularity due to its non-invasive sampling technique. Fasting (abstinence from food or drink or both) research for weight loss and improve health is common, but studies using fasting saliva are scarce. Some metabolites in fasting saliva have been reported with interesting results, which can be enhanced by considering different confounding factors. For example, fasting saliva contains higher salivary nitrite, which is related to nitric oxide (NO). NO is a vasodilator supporting the healthy function of endothelial cells and its deficiency is connected to many diseases. The timely supply of NO through exogenous and endogenous means is highlighted and the potential advantage of fasting salivary composition changes in relation to COVID-19 infection is speculated. This review aims to provide a general discussion on the salivary composition, properties, and functions of the whole saliva, including the health benefits of fasting.http://www.sciencedirect.com/science/article/pii/S2213453023001416SalivaFastingRamadanNitrateNitriteNitric Oxide |
| spellingShingle | Nurul Fadhilah Kamalul Aripin N. Idayu Zahid Mohd Aizat Abdul Rahim Hashim Yaacob Parvez I. Haris Zubaidah Haji Abd. Rahim Rauzah Hashim A review of salivary composition changes induced by fasting and its impact on health Food Science and Human Wellness Saliva Fasting Ramadan Nitrate Nitrite Nitric Oxide |
| title | A review of salivary composition changes induced by fasting and its impact on health |
| title_full | A review of salivary composition changes induced by fasting and its impact on health |
| title_fullStr | A review of salivary composition changes induced by fasting and its impact on health |
| title_full_unstemmed | A review of salivary composition changes induced by fasting and its impact on health |
| title_short | A review of salivary composition changes induced by fasting and its impact on health |
| title_sort | review of salivary composition changes induced by fasting and its impact on health |
| topic | Saliva Fasting Ramadan Nitrate Nitrite Nitric Oxide |
| url | http://www.sciencedirect.com/science/article/pii/S2213453023001416 |
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