Temporal trends of the incidence rate of syphilis during pregnancy and congenital syphilis in São Paulo, Brazil, 2011-2023
ABSTRACT Objective To analyze trends of syphilis during pregnancy and congenital syphilis, based on reported cases in São Paulo, Brazil, from 2011 to 2023. Methods Ecological time series study, based on data from Notifiable Health Conditions Information System records. The Prais-Winsten method was...
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Ministério da Saúde do Brasil
2025-01-01
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| Series: | Epidemiologia e Serviços de Saúde |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-96222024000100239&lng=en&tlng=en |
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| author | Beatriz Poddis Busquim e Silva Fernanda Penido Matozinhos Rafaela Siqueira Costa Schreck Fernanda Marçal Ferreira Camilla Pontes Bezerra Bárbara Tideman Sartório Camargo Thales Philipe Rodrigues da Silva |
| author_facet | Beatriz Poddis Busquim e Silva Fernanda Penido Matozinhos Rafaela Siqueira Costa Schreck Fernanda Marçal Ferreira Camilla Pontes Bezerra Bárbara Tideman Sartório Camargo Thales Philipe Rodrigues da Silva |
| author_sort | Beatriz Poddis Busquim e Silva |
| collection | DOAJ |
| description | ABSTRACT Objective To analyze trends of syphilis during pregnancy and congenital syphilis, based on reported cases in São Paulo, Brazil, from 2011 to 2023. Methods Ecological time series study, based on data from Notifiable Health Conditions Information System records. The Prais-Winsten method was used to verify trends. Results 125,776 cases of syphilis during pregnancy and 42,418 cases of congenital syphilis were reported. Average annual percentage change (95%CI) in the syphilis during pregnancy incidence rate was 18.68 (95%CI 16.57; 20.84), pvalue < 0.001; while for congenital syphilis it was 11.99 (95%CI 7.00; 17.22), p-value < 0.001. Conclusion Incidence rates of syphilis during pregnancy and congenital syphilis showed significant increasing trends, which may be related to the increase in the former during the diagnosis period (1st trimester), demonstrating increased testing among pregnant women, clinical classification at the time of diagnosis (latent syphilis), as well as inefficiency of adequate treatment when diagnosis is late. |
| format | Article |
| id | doaj-art-892d351623474b58a60b1505361e4352 |
| institution | Kabale University |
| issn | 2237-9622 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Ministério da Saúde do Brasil |
| record_format | Article |
| series | Epidemiologia e Serviços de Saúde |
| spelling | doaj-art-892d351623474b58a60b1505361e43522025-02-04T07:39:06ZengMinistério da Saúde do BrasilEpidemiologia e Serviços de Saúde2237-96222025-01-013310.1590/s2237-96222024v33e2024637.enTemporal trends of the incidence rate of syphilis during pregnancy and congenital syphilis in São Paulo, Brazil, 2011-2023Beatriz Poddis Busquim e Silvahttps://orcid.org/0000-0002-9975-4472Fernanda Penido Matozinhoshttps://orcid.org/0000-0003-1368-4248Rafaela Siqueira Costa Schreckhttps://orcid.org/0000-0001-5251-3973Fernanda Marçal Ferreirahttps://orcid.org/0000-0003-3383-1540Camilla Pontes Bezerrahttps://orcid.org/0000-0002-9564-5623Bárbara Tideman Sartório Camargohttps://orcid.org/0000-0003-3644-0350Thales Philipe Rodrigues da Silvahttps://orcid.org/0000-0002-7115-0925ABSTRACT Objective To analyze trends of syphilis during pregnancy and congenital syphilis, based on reported cases in São Paulo, Brazil, from 2011 to 2023. Methods Ecological time series study, based on data from Notifiable Health Conditions Information System records. The Prais-Winsten method was used to verify trends. Results 125,776 cases of syphilis during pregnancy and 42,418 cases of congenital syphilis were reported. Average annual percentage change (95%CI) in the syphilis during pregnancy incidence rate was 18.68 (95%CI 16.57; 20.84), pvalue < 0.001; while for congenital syphilis it was 11.99 (95%CI 7.00; 17.22), p-value < 0.001. Conclusion Incidence rates of syphilis during pregnancy and congenital syphilis showed significant increasing trends, which may be related to the increase in the former during the diagnosis period (1st trimester), demonstrating increased testing among pregnant women, clinical classification at the time of diagnosis (latent syphilis), as well as inefficiency of adequate treatment when diagnosis is late.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-96222024000100239&lng=en&tlng=enSyphilisSyphilis, CongenitalPregnant WomenEpidemiological MonitoringSexually Transmitted Diseases |
| spellingShingle | Beatriz Poddis Busquim e Silva Fernanda Penido Matozinhos Rafaela Siqueira Costa Schreck Fernanda Marçal Ferreira Camilla Pontes Bezerra Bárbara Tideman Sartório Camargo Thales Philipe Rodrigues da Silva Temporal trends of the incidence rate of syphilis during pregnancy and congenital syphilis in São Paulo, Brazil, 2011-2023 Epidemiologia e Serviços de Saúde Syphilis Syphilis, Congenital Pregnant Women Epidemiological Monitoring Sexually Transmitted Diseases |
| title | Temporal trends of the incidence rate of syphilis during pregnancy and congenital syphilis in São Paulo, Brazil, 2011-2023 |
| title_full | Temporal trends of the incidence rate of syphilis during pregnancy and congenital syphilis in São Paulo, Brazil, 2011-2023 |
| title_fullStr | Temporal trends of the incidence rate of syphilis during pregnancy and congenital syphilis in São Paulo, Brazil, 2011-2023 |
| title_full_unstemmed | Temporal trends of the incidence rate of syphilis during pregnancy and congenital syphilis in São Paulo, Brazil, 2011-2023 |
| title_short | Temporal trends of the incidence rate of syphilis during pregnancy and congenital syphilis in São Paulo, Brazil, 2011-2023 |
| title_sort | temporal trends of the incidence rate of syphilis during pregnancy and congenital syphilis in sao paulo brazil 2011 2023 |
| topic | Syphilis Syphilis, Congenital Pregnant Women Epidemiological Monitoring Sexually Transmitted Diseases |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-96222024000100239&lng=en&tlng=en |
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