Substrates, regulation, cellular functions, and disease associations of P4-ATPases
Abstract P4-ATPases, a subfamily of the P-type ATPase superfamily, play a crucial role in translocating membrane lipids from the exoplasmic/luminal leaflet to the cytoplasmic leaflet. This process generates and regulates transbilayer lipid asymmetry. These enzymes are conserved across all eukaryotes...
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Main Authors: | Hye-Won Shin, Hiroyuki Takatsu |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-025-07549-3 |
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