Optimizing T cell transduction: a novel transduction device for efficient and scalable gene delivery

Abstract Background Viral transduction is a critical step in the manufacturing of genetically modified T cells for immunotherapies, yet conventional transduction methods suffer from low to medium efficiency, high vector consumption, and limited scalability. Methods To address these challenges, we in...

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Bibliographic Details
Main Authors: Kang-Zheng Lee, Tan Dai Nguyen, Dan Liu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06836-1
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