Stress-Induced Depression and Its Effects on Tooth Wear in Rats: A 3D Dental Scan Imaging Perspective
Background: In addition to behavioral and biochemical abnormalities, a parafunction associated with temporomandibular joint disorders (TMDs) resulted in stress-induced depression in rats. Exploring how chronic stress influences molar wear in rodents provides insights into the understanding of depres...
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2025-04-01
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| author | Preeyarat Plongniras Sarawut Lapmanee Natchayaporn Thonapan Phuripong Thangsombat Phongsakorn Janthaphim Chanakarn Lertkarnvijai Pattama Chailertvanitkul Supawich Morkmued |
| author_facet | Preeyarat Plongniras Sarawut Lapmanee Natchayaporn Thonapan Phuripong Thangsombat Phongsakorn Janthaphim Chanakarn Lertkarnvijai Pattama Chailertvanitkul Supawich Morkmued |
| author_sort | Preeyarat Plongniras |
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| description | Background: In addition to behavioral and biochemical abnormalities, a parafunction associated with temporomandibular joint disorders (TMDs) resulted in stress-induced depression in rats. Exploring how chronic stress influences molar wear in rodents provides insights into the understanding of depression, TMD, and oral health. This study aimed to conduct a three-dimensional (3D) analysis of first molar wear in an animal model of depression by comparing molar attrition and cusp variation between stressed male rats and control groups. Methods: After obtaining a validated model of depression in male rats, we obtained 3D scans of lower molars to analyze wear patterns. The 3D analysis was applied to quantify cusps’ volume and the difference in first molar cusp morphological structure. The data were then compared to identify significant morphological differences between groups side by side. Results: The analysis revealed the reduction of cusps’ volume in the depression groups. Rats exposed to depression exhibited significantly greater occlusal table wear than their control counterparts (<i>p</i> < 0.05). Conclusions: As dentistry moves towards greater digital imaging, understanding the impact of psychological factors on TMD becomes increasingly necessary. This study shows that stress-induced depression in rats can result in significant tooth wear, as investigated using a 3D dental scanner. |
| format | Article |
| id | doaj-art-88e40d7824c74e4988393c7d90b8cfa0 |
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| issn | 2075-1729 |
| language | English |
| publishDate | 2025-04-01 |
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| spelling | doaj-art-88e40d7824c74e4988393c7d90b8cfa02025-08-20T01:56:16ZengMDPI AGLife2075-17292025-04-0115571210.3390/life15050712Stress-Induced Depression and Its Effects on Tooth Wear in Rats: A 3D Dental Scan Imaging PerspectivePreeyarat Plongniras0Sarawut Lapmanee1Natchayaporn Thonapan2Phuripong Thangsombat3Phongsakorn Janthaphim4Chanakarn Lertkarnvijai5Pattama Chailertvanitkul6Supawich Morkmued7Department of Prosthodontics, Faculty of Dentistry, Khon Kaen University, Khon Kaen 40002, ThailandChulabhorn International College of Medicine, Thammasat University, Pathum Thani 12120, ThailandDepartment of Radiological Technology, Faculty of Allied Health Sciences, Thammasat University, Pathum Thani 12120, ThailandDepartment of Preventive Dentistry, Pediatric Dentistry Division, Faculty of Dentistry, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Preventive Dentistry, Pediatric Dentistry Division, Faculty of Dentistry, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Preventive Dentistry, Pediatric Dentistry Division, Faculty of Dentistry, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Restorative Dentistry, Faculty of Dentistry, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Preventive Dentistry, Pediatric Dentistry Division, Faculty of Dentistry, Khon Kaen University, Khon Kaen 40002, ThailandBackground: In addition to behavioral and biochemical abnormalities, a parafunction associated with temporomandibular joint disorders (TMDs) resulted in stress-induced depression in rats. Exploring how chronic stress influences molar wear in rodents provides insights into the understanding of depression, TMD, and oral health. This study aimed to conduct a three-dimensional (3D) analysis of first molar wear in an animal model of depression by comparing molar attrition and cusp variation between stressed male rats and control groups. Methods: After obtaining a validated model of depression in male rats, we obtained 3D scans of lower molars to analyze wear patterns. The 3D analysis was applied to quantify cusps’ volume and the difference in first molar cusp morphological structure. The data were then compared to identify significant morphological differences between groups side by side. Results: The analysis revealed the reduction of cusps’ volume in the depression groups. Rats exposed to depression exhibited significantly greater occlusal table wear than their control counterparts (<i>p</i> < 0.05). Conclusions: As dentistry moves towards greater digital imaging, understanding the impact of psychological factors on TMD becomes increasingly necessary. This study shows that stress-induced depression in rats can result in significant tooth wear, as investigated using a 3D dental scanner.https://www.mdpi.com/2075-1729/15/5/712depressionrestraint stresstooth wearbruxismtemporomandibular disorderdental digital scanner |
| spellingShingle | Preeyarat Plongniras Sarawut Lapmanee Natchayaporn Thonapan Phuripong Thangsombat Phongsakorn Janthaphim Chanakarn Lertkarnvijai Pattama Chailertvanitkul Supawich Morkmued Stress-Induced Depression and Its Effects on Tooth Wear in Rats: A 3D Dental Scan Imaging Perspective Life depression restraint stress tooth wear bruxism temporomandibular disorder dental digital scanner |
| title | Stress-Induced Depression and Its Effects on Tooth Wear in Rats: A 3D Dental Scan Imaging Perspective |
| title_full | Stress-Induced Depression and Its Effects on Tooth Wear in Rats: A 3D Dental Scan Imaging Perspective |
| title_fullStr | Stress-Induced Depression and Its Effects on Tooth Wear in Rats: A 3D Dental Scan Imaging Perspective |
| title_full_unstemmed | Stress-Induced Depression and Its Effects on Tooth Wear in Rats: A 3D Dental Scan Imaging Perspective |
| title_short | Stress-Induced Depression and Its Effects on Tooth Wear in Rats: A 3D Dental Scan Imaging Perspective |
| title_sort | stress induced depression and its effects on tooth wear in rats a 3d dental scan imaging perspective |
| topic | depression restraint stress tooth wear bruxism temporomandibular disorder dental digital scanner |
| url | https://www.mdpi.com/2075-1729/15/5/712 |
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