Quantification of total sBCMA in human plasma by peptide-level immunocapture LC-MS/MS

Background: B-cell maturation antigen (BCMA) is a membrane protein that is overexpressed in multiple myeloma cells and can be targeted with biotherapeutic agents. BCMA is naturally shed by γ-secretase, leading to the formation of soluble BCMA (sBCMA), which circulates in the blood. sBCMA can affect...

Full description

Saved in:
Bibliographic Details
Main Authors: Johanna Paris, Alexandra Tavernier, Sylvie Bethegnies, Sandrine Descloux, Olivier Fedeli
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Journal of Mass Spectrometry and Advances in the Clinical Lab
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667145X25000136
Tags: Add Tag
No Tags, Be the first to tag this record!