Dynamical mechanisms of growth-feedback effects on adaptive gene circuits
The successful integration of engineered gene circuits into host cells remains a significant challenge in synthetic biology due to circuit–host interactions, such as growth feedback, where the circuit influences cell growth and vice versa. Understanding the dynamics of circuit failures and identifyi...
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| Main Authors: | Ling-Wei Kong, Wenjia Shi, Xiao-Jun Tian, Ying-Cheng Lai |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2025-06-01
|
| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/89170 |
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