Dynamical mechanisms of growth-feedback effects on adaptive gene circuits

The successful integration of engineered gene circuits into host cells remains a significant challenge in synthetic biology due to circuit–host interactions, such as growth feedback, where the circuit influences cell growth and vice versa. Understanding the dynamics of circuit failures and identifyi...

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Bibliographic Details
Main Authors: Ling-Wei Kong, Wenjia Shi, Xiao-Jun Tian, Ying-Cheng Lai
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-06-01
Series:eLife
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Online Access:https://elifesciences.org/articles/89170
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