Nonsecretory Multiple Myeloma and AL Amyloidosis Presenting with Nephrotic Range Proteinuria
Nonsecretory multiple myeloma (NSMM) is the absence of a detectable monoclonal protein in serum and urine of a multiple myeloma (MM) patient and immunoglobulin light chain (AL) amyloidosis is a significantly rare complication. A case of NSMM with AL amyloidosis and nephrotic range proteinuria is pre...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2015/635974 |
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| author | Ozlem Beyler Kilic Ali Kemal Oguz Ihsan Ergun Dilek Ertoy Baydar Meltem Ayli |
| author_facet | Ozlem Beyler Kilic Ali Kemal Oguz Ihsan Ergun Dilek Ertoy Baydar Meltem Ayli |
| author_sort | Ozlem Beyler Kilic |
| collection | DOAJ |
| description | Nonsecretory multiple myeloma (NSMM) is the absence of a detectable monoclonal protein in serum and urine of a multiple myeloma (MM) patient and immunoglobulin light chain (AL) amyloidosis is a significantly rare complication. A case of NSMM with AL amyloidosis and nephrotic range proteinuria is presented. Sharing clinical, therapeutic, and prognostic characteristics with MM, real challenge may be during initial diagnosis of NSMM and assessment of treatment response. In elderly patients with unexplained renal dysfunction, MM should be in the differential diagnosis and the absence of a monoclonal protein should not rule out MM but should remind us of the possibility of NSMM. |
| format | Article |
| id | doaj-art-889836a40acb41c981f454e80840d54d |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-889836a40acb41c981f454e80840d54d2025-02-03T05:51:07ZengWileyCase Reports in Nephrology2090-66412090-665X2015-01-01201510.1155/2015/635974635974Nonsecretory Multiple Myeloma and AL Amyloidosis Presenting with Nephrotic Range ProteinuriaOzlem Beyler Kilic0Ali Kemal Oguz1Ihsan Ergun2Dilek Ertoy Baydar3Meltem Ayli4Department of Internal Medicine, Ufuk University School of Medicine, 06520 Ankara, TurkeyDepartment of Internal Medicine, Ufuk University School of Medicine, 06520 Ankara, TurkeyDivision of Nephrology, Department of Internal Medicine, Ufuk University School of Medicine, 06520 Ankara, TurkeyDepartment of Pathology, Hacettepe University School of Medicine, 06100 Ankara, TurkeyDivision of Hematology, Department of Internal Medicine, Ufuk University School of Medicine, 06520 Ankara, TurkeyNonsecretory multiple myeloma (NSMM) is the absence of a detectable monoclonal protein in serum and urine of a multiple myeloma (MM) patient and immunoglobulin light chain (AL) amyloidosis is a significantly rare complication. A case of NSMM with AL amyloidosis and nephrotic range proteinuria is presented. Sharing clinical, therapeutic, and prognostic characteristics with MM, real challenge may be during initial diagnosis of NSMM and assessment of treatment response. In elderly patients with unexplained renal dysfunction, MM should be in the differential diagnosis and the absence of a monoclonal protein should not rule out MM but should remind us of the possibility of NSMM.http://dx.doi.org/10.1155/2015/635974 |
| spellingShingle | Ozlem Beyler Kilic Ali Kemal Oguz Ihsan Ergun Dilek Ertoy Baydar Meltem Ayli Nonsecretory Multiple Myeloma and AL Amyloidosis Presenting with Nephrotic Range Proteinuria Case Reports in Nephrology |
| title | Nonsecretory Multiple Myeloma and AL Amyloidosis Presenting with Nephrotic Range Proteinuria |
| title_full | Nonsecretory Multiple Myeloma and AL Amyloidosis Presenting with Nephrotic Range Proteinuria |
| title_fullStr | Nonsecretory Multiple Myeloma and AL Amyloidosis Presenting with Nephrotic Range Proteinuria |
| title_full_unstemmed | Nonsecretory Multiple Myeloma and AL Amyloidosis Presenting with Nephrotic Range Proteinuria |
| title_short | Nonsecretory Multiple Myeloma and AL Amyloidosis Presenting with Nephrotic Range Proteinuria |
| title_sort | nonsecretory multiple myeloma and al amyloidosis presenting with nephrotic range proteinuria |
| url | http://dx.doi.org/10.1155/2015/635974 |
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